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- T_cell_receptor abstract "The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen is of relatively low affinity and is degenerate: that is, many TCR recognize the same antigen and many antigens are recognized by the same TCR.The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) and beta (β) chain, whereas in 5% of T cells this consists of gamma and delta (γ/δ) chains. This ratio changes during ontogeny and in diseased states.When the TCR engages with antigenic peptide and MHC (peptide/MHC), the T lymphocyte is activated through a series of biochemical events mediated by associated enzymes, co-receptors, specialized adaptor molecules, and activated or released transcription factors.".
- T_cell_receptor arm "q".
- T_cell_receptor band "11.2".
- T_cell_receptor band "34".
- T_cell_receptor chromosome "14".
- T_cell_receptor chromosome "7".
- T_cell_receptor entrezgene "6955".
- T_cell_receptor entrezgene "6957".
- T_cell_receptor hgncid "12027".
- T_cell_receptor hgncid "12155".
- T_cell_receptor omim "186880".
- T_cell_receptor omim "186930".
- T_cell_receptor symbol "TCRA".
- T_cell_receptor symbol "TCRB".
- T_cell_receptor symbol "TRA@".
- T_cell_receptor symbol "TRB@".
- T_cell_receptor thumbnail TCRComplex.png?width=300.
- T_cell_receptor wikiPageExternalLink abTCR.
- T_cell_receptor wikiPageID "2060539".
- T_cell_receptor wikiPageRevisionID "639857485".
- T_cell_receptor altsymbols "TCRA".
- T_cell_receptor altsymbols "TCRB".
- T_cell_receptor arm "q".
- T_cell_receptor band "11.2".
- T_cell_receptor band "34".
- T_cell_receptor caption "The T-cell receptor complex with TCR-α and TCR-β chains, CD3 and ζ-chain accessory molecules.".
- T_cell_receptor chromosome "14".
- T_cell_receptor chromosome "7".
- T_cell_receptor entrezgene "6955".
- T_cell_receptor entrezgene "6957".
- T_cell_receptor hgncid "12027".
- T_cell_receptor hgncid "12155".
- T_cell_receptor interpro "IPR021663".
- T_cell_receptor name "T cell receptor alpha locus".
- T_cell_receptor name "T cell receptor beta locus".
- T_cell_receptor omim "186880".
- T_cell_receptor omim "186930".
- T_cell_receptor opmFamily "261".
- T_cell_receptor opmProtein "2".
- T_cell_receptor pfam "PF11628".
- T_cell_receptor symbol "TRA@".
- T_cell_receptor symbol "TRB@".
- T_cell_receptor subject Category:Cell_signaling.
- T_cell_receptor subject Category:Integral_membrane_proteins.
- T_cell_receptor subject Category:T_cells.
- T_cell_receptor type Biomolecule.
- T_cell_receptor type Protein.
- T_cell_receptor type Thing.
- T_cell_receptor type Q206229.
- T_cell_receptor type Q8054.
- T_cell_receptor comment "The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen is of relatively low affinity and is degenerate: that is, many TCR recognize the same antigen and many antigens are recognized by the same TCR.The TCR is composed of two different protein chains (that is, it is a heterodimer).".
- T_cell_receptor label "Receptor de células T".
- T_cell_receptor label "Receptor de linfocitos T".
- T_cell_receptor label "Receptor dels limfòcits T".
- T_cell_receptor label "Receptor limfocytów T".
- T_cell_receptor label "Récepteur des cellules T".
- T_cell_receptor label "T cell receptor".
- T_cell_receptor label "T-Zell-Rezeptor".
- T_cell_receptor label "T-buněčný receptor".
- T_cell_receptor label "T-cell receptor".
- T_cell_receptor label "T細胞受容体".
- T_cell_receptor label "Т-клеточный рецептор".
- T_cell_receptor sameAs T-buněčný_receptor.
- T_cell_receptor sameAs T-Zell-Rezeptor.
- T_cell_receptor sameAs Receptor_de_linfocitos_T.
- T_cell_receptor sameAs Récepteur_des_cellules_T.
- T_cell_receptor sameAs T-cell_receptor.
- T_cell_receptor sameAs T細胞受容体.
- T_cell_receptor sameAs Receptor_limfocytów_T.
- T_cell_receptor sameAs Receptor_de_células_T.
- T_cell_receptor sameAs m.06j9qn.
- T_cell_receptor sameAs Q412037.
- T_cell_receptor sameAs Q412037.
- T_cell_receptor wasDerivedFrom T_cell_receptor?oldid=639857485.
- T_cell_receptor depiction TCRComplex.png.
- T_cell_receptor isPrimaryTopicOf T_cell_receptor.
- T_cell_receptor name "T cell receptor alpha locus".
- T_cell_receptor name "T cell receptor beta locus".