Matches in DBpedia 2015-04 for { <http://dbpedia.org/resource/Mitotane> ?p ?o }
Showing triples 1 to 89 of
89
with 100 triples per page.
- Mitotane abstract "Mitotane, also known as o,p'-DDD (Lysodren), is an antineoplastic medication used in the treatment of adrenocortical carcinoma. It is an isomer of DDD and is a derivative of DDT. Its main use is in those patients who have persistent disease despite surgical resection, those who are not surgical candidates, or those who have metastatic disease. It has been produced by Bristol Myers Squibb SpA but it is marketed as an orphan drug due to the small number of patients in need of it. A 2007 study of 177 patients shows a significant increase in the recurrence-free interval after radical surgery followed by mitotane when compared to surgery alone.Mitotane alters steroid peripheral metabolism, directly suppresses the adrenal cortex and alters cortisone metabolism leading to hypocortisolism. Side effects as reported by Schteinberg et al. include anorexia and nausea (88%), diarrhea (38%), vomiting (23%), decreased memory and ability to concentrate (50%), rash (23%), gynecomastia (50%), arthralgia (19%), and leukopenia (7%).Its trade name is Lysodren.".
- Mitotane atcPrefix "L01".
- Mitotane atcSuffix "XX23".
- Mitotane bioavailability "40.0".
- Mitotane casNumber "53-19-0".
- Mitotane drugbank "DB00648".
- Mitotane fdaUniiCode "78E4J5IB5J".
- Mitotane iupacName "(RS)-1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)-ethyl]-benzene".
- Mitotane pubchem "4211".
- Mitotane thumbnail Mitotane.svg?width=300.
- Mitotane wikiPageExternalLink 53-19-0-eng.php.
- Mitotane wikiPageExternalLink RM%20Scope_B12%20-%2053-19-0_EN.pdf.
- Mitotane wikiPageExternalLink wqjmv74186x57wx1.
- Mitotane wikiPageID "3818785".
- Mitotane wikiPageRevisionID "643367583".
- Mitotane atcPrefix "L01".
- Mitotane atcSuffix "XX23".
- Mitotane bioavailability "40.0".
- Mitotane c "14".
- Mitotane casNumber "53".
- Mitotane chembl "1670".
- Mitotane chemspiderid "4066".
- Mitotane cl "4".
- Mitotane drugName "Mitotane".
- Mitotane drugbank "DB00648".
- Mitotane eliminationHalfLife "1.37376E7".
- Mitotane h "10".
- Mitotane hasPhotoCollection Mitotane.
- Mitotane imagename "1".
- Mitotane inchi "1".
- Mitotane inchikey "JWBOIMRXGHLCPP-UHFFFAOYAD".
- Mitotane iupacName "-1".
- Mitotane kegg "D00420".
- Mitotane legalStatus "Rx-only".
- Mitotane licenceUs "MITOTANE".
- Mitotane medlineplus "a608050".
- Mitotane molecularWeight "320.04".
- Mitotane pregnancyCategory "C".
- Mitotane proteinBound "6.0".
- Mitotane pubchem "4211".
- Mitotane routesOfAdministration "Oral".
- Mitotane smiles "Clc1ccccc1CCCl".
- Mitotane stdinchi "1".
- Mitotane stdinchikey "JWBOIMRXGHLCPP-UHFFFAOYSA-N".
- Mitotane tradename "Lysodren".
- Mitotane unii "780000".
- Mitotane verifiedrevid "462252859".
- Mitotane width "200".
- Mitotane subject Category:Antiglucocorticoids.
- Mitotane subject Category:Antineoplastic_drugs.
- Mitotane subject Category:Organochlorides.
- Mitotane subject Category:Orphan_drugs.
- Mitotane subject Category:Steroid_11%CE%B2-hydroxylase_inhibitors.
- Mitotane type Agent114778436.
- Mitotane type Antineoplastic102722458.
- Mitotane type AntineoplasticDrugs.
- Mitotane type CausalAgent100007347.
- Mitotane type CytotoxicDrug103157987.
- Mitotane type Drug103247620.
- Mitotane type Matter100020827.
- Mitotane type Medicine103740161.
- Mitotane type OrphanDrugs.
- Mitotane type PhysicalEntity100001930.
- Mitotane type Substance100020090.
- Mitotane type Drug.
- Mitotane type DrugProduct.
- Mitotane type Thing.
- Mitotane type Q8386.
- Mitotane comment "Mitotane, also known as o,p'-DDD (Lysodren), is an antineoplastic medication used in the treatment of adrenocortical carcinoma. It is an isomer of DDD and is a derivative of DDT. Its main use is in those patients who have persistent disease despite surgical resection, those who are not surgical candidates, or those who have metastatic disease. It has been produced by Bristol Myers Squibb SpA but it is marketed as an orphan drug due to the small number of patients in need of it.".
- Mitotane label "Mitotan".
- Mitotane label "Mitotan".
- Mitotane label "Mitotane".
- Mitotane label "Mitotane".
- Mitotane label "ミトタン".
- Mitotane sameAs Mitotan.
- Mitotane sameAs ミトタン.
- Mitotane sameAs Mitotane.
- Mitotane sameAs Mitotan.
- Mitotane sameAs m.0b1l9y.
- Mitotane sameAs Q417465.
- Mitotane sameAs Q417465.
- Mitotane sameAs mitotane.
- Mitotane sameAs DB00648.
- Mitotane sameAs 4211.
- Mitotane sameAs Mitotane.
- Mitotane wasDerivedFrom Mitotane?oldid=643367583.
- Mitotane depiction Mitotane.svg.
- Mitotane isPrimaryTopicOf Mitotane.
- Mitotane name "Mitotane".