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- Methoctramine abstract "Methoctramine is a polymethylene tetraamine that acts as a muscarinic antagonist. It preferently binds to the pre-synaptic receptor M2, a muscarinic acetylcholine ganglionic protein complex present basically in heart cells. In normal conditions -absence of methoctramine-, the activation of M2 receptors diminishes the speed of conduction of the sinoatrial and atrioventricular nodes thus reducing the heart rate. Thanks to its apparently high cardioselectivity, it has been studied as a potential parasymphatolitic drug, particularly against bradychardia. However, currently it’s only addressed for research purposes, since the administration to humans is still unavailable.".
- Methoctramine casNumber "104807-46-7".
- Methoctramine chEBI "73339".
- Methoctramine iupacName "N, N'-bis[6-[(2-methoxybenzyl)amino]hexyl]-1, 8-octanediamine".
- Methoctramine pubchem "4108".
- Methoctramine thumbnail Methoctramine.svg?width=300.
- Methoctramine wikiPageID "44174354".
- Methoctramine wikiPageRevisionID "639681080".
- Methoctramine c "36".
- Methoctramine casNumber "104807".
- Methoctramine chebi "73339".
- Methoctramine chemspiderid "3965".
- Methoctramine h "62".
- Methoctramine image "Methoctramine.jpg".
- Methoctramine iupacName "N, N'-bis[6-[amino]hexyl]-1, 8-octanediamine".
- Methoctramine legalUs "Only for research".
- Methoctramine molecularWeight "582.9".
- Methoctramine n "4".
- Methoctramine o "2".
- Methoctramine pubchem "4108".
- Methoctramine smiles "COC1=CC=CC=C1CNCCCCCCNCCCCCCCCNCCCCCCNCC2=CC=CC=C2OC".
- Methoctramine solubility "20".
- Methoctramine stdinchi "1".
- Methoctramine subject Category:Muscarinic_antagonists.
- Methoctramine subject Category:Polyamines.
- Methoctramine type Drug.
- Methoctramine type Thing.
- Methoctramine type Q8386.
- Methoctramine comment "Methoctramine is a polymethylene tetraamine that acts as a muscarinic antagonist. It preferently binds to the pre-synaptic receptor M2, a muscarinic acetylcholine ganglionic protein complex present basically in heart cells. In normal conditions -absence of methoctramine-, the activation of M2 receptors diminishes the speed of conduction of the sinoatrial and atrioventricular nodes thus reducing the heart rate.".
- Methoctramine label "Methoctramine".
- Methoctramine sameAs m.0125p5yt.
- Methoctramine sameAs Q18344124.
- Methoctramine sameAs Q18344124.
- Methoctramine wasDerivedFrom Methoctramine?oldid=639681080.
- Methoctramine depiction Methoctramine.svg.
- Methoctramine isPrimaryTopicOf Methoctramine.