Matches in DBpedia 2015-04 for { <http://dbpedia.org/resource/Cerivastatin> ?p ?o }
Showing triples 1 to 75 of
75
with 100 triples per page.
- Cerivastatin abstract "Cerivastatin (brand names: Baycol, Lipobay) is a synthetic member of the class of statins used to lower cholesterol and prevent cardiovascular disease. It was marketed by the pharmaceutical company Bayer A.G. in the late 1990s, competing with Pfizer's highly successful atorvastatin (Lipitor). Cerivastatin was voluntarily withdrawn from the market worldwide in 2001, due to reports of fatal rhabdomyolysis.During postmarketing surveillance, 52 deaths were reported in patients using cerivastatin, mainly from rhabdomyolysis and its resultant renal failure. Risks were higher in patients using fibrates, mainly gemfibrozil (Lopid), and in patients using the highest (0.8 mg/day) dose of cerivastatin. Bayer A.G. added a contraindication for the concomitant use of cerivastatin and gemfibrozil to the package 18 months after the drug interaction was found. The frequency of deadly cases of rhabdomyolysis with cerivastatin was 16 to 80 times higher than with other statins. Another 385 nonfatal cases of rhabdomyolysis were reported. This put the risk of this (rare) complication at 5-10 times that of the other statins. Cerivastatin also induced myopathy in a dose-dependent manner when administered as monotherapy, but that was revealed only after Bayer was sued and unpublished company documents were opened.".
- Cerivastatin atcPrefix "C10".
- Cerivastatin atcSuffix "AA06".
- Cerivastatin casNumber "145599-86-6".
- Cerivastatin chEBI "3558".
- Cerivastatin drugbank "DB00439".
- Cerivastatin fdaUniiCode "AM91H2KS67".
- Cerivastatin iupacName "(3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid".
- Cerivastatin pubchem "446156".
- Cerivastatin thumbnail Cerivastatin2DCSD.svg?width=300.
- Cerivastatin wikiPageID "637177".
- Cerivastatin wikiPageRevisionID "608633088".
- Cerivastatin atcPrefix "10.0".
- Cerivastatin atcSuffix "AA06".
- Cerivastatin c "26".
- Cerivastatin casNumber "145599".
- Cerivastatin chebi "3558".
- Cerivastatin chembl "1477".
- Cerivastatin chemspiderid "393588".
- Cerivastatin drugbank "DB00439".
- Cerivastatin eliminationHalfLife "10800.0".
- Cerivastatin f "1".
- Cerivastatin h "34".
- Cerivastatin hasPhotoCollection Cerivastatin.
- Cerivastatin inchi "1".
- Cerivastatin inchikey "SEERZIQQUAZTOL-ANMDKAQQBT".
- Cerivastatin iupacName "-7".
- Cerivastatin kegg "D07661".
- Cerivastatin legalStatus "Withdrawn from market".
- Cerivastatin molecularWeight "459.55".
- Cerivastatin n "1".
- Cerivastatin o "5".
- Cerivastatin pregnancyAu "D".
- Cerivastatin pubchem "446156".
- Cerivastatin smiles "O=CC[C@H]C[C@H]/C=C/c1cCC".
- Cerivastatin stdinchi "1".
- Cerivastatin stdinchikey "SEERZIQQUAZTOL-ANMDKAQQSA-N".
- Cerivastatin unii "AM91H2KS67".
- Cerivastatin verifiedfields "changed".
- Cerivastatin verifiedrevid "460025724".
- Cerivastatin width "180".
- Cerivastatin subject Category:Carboxylic_acids.
- Cerivastatin subject Category:Diols.
- Cerivastatin subject Category:Ethers.
- Cerivastatin subject Category:Organofluorides.
- Cerivastatin subject Category:Pyridines.
- Cerivastatin subject Category:Statins.
- Cerivastatin subject Category:Withdrawn_drugs.
- Cerivastatin type Drug.
- Cerivastatin type DrugProduct.
- Cerivastatin type Thing.
- Cerivastatin type Q8386.
- Cerivastatin comment "Cerivastatin (brand names: Baycol, Lipobay) is a synthetic member of the class of statins used to lower cholesterol and prevent cardiovascular disease. It was marketed by the pharmaceutical company Bayer A.G. in the late 1990s, competing with Pfizer's highly successful atorvastatin (Lipitor).".
- Cerivastatin label "Cerivastatin".
- Cerivastatin label "Cerivastatin".
- Cerivastatin label "Cerivastatina".
- Cerivastatin label "Cerivastatina".
- Cerivastatin label "Cerivastatina".
- Cerivastatin label "Cerivastatine".
- Cerivastatin label "Cérivastatine".
- Cerivastatin sameAs Cerivastatin.
- Cerivastatin sameAs Cerivastatina.
- Cerivastatin sameAs Cérivastatine.
- Cerivastatin sameAs Cerivastatina.
- Cerivastatin sameAs Cerivastatine.
- Cerivastatin sameAs Ceriwastatyna.
- Cerivastatin sameAs Cerivastatina.
- Cerivastatin sameAs m.02z9d3.
- Cerivastatin sameAs Q423439.
- Cerivastatin sameAs Q423439.
- Cerivastatin sameAs DB00439.
- Cerivastatin sameAs 2676.
- Cerivastatin wasDerivedFrom Cerivastatin?oldid=608633088.
- Cerivastatin depiction Cerivastatin2DCSD.svg.
- Cerivastatin isPrimaryTopicOf Cerivastatin.