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- Abecarnil abstract "Abecarnil (ZK-112,119) is an anxiolytic drug from the β-Carboline family. It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures. It is a partial agonist acting selectively at the benzodiazepine site of the GABAA receptor.Abecarnil was originally developed as an anti-anxiety drug, but has not as yet been commercially developed for use in humans, instead so far mainly being used for research into the development of other new sedative and anxiolytic drugs. Investigations are continuing into its actions and it looks likely to be developed for use both in the treatment of anxiety, and as a less addictive substitute drug for the treatment of benzodiazepine and alcohol addiction. Abecarnil may also have less problems of tolerance and withdrawal problems compared to nonselective full agonist benzodiazepine acting drugs.Abecarnil is a relatively subtype-selective drug which produces primarily anxiolytic effects, with comparatively less sedative or muscle relaxant properties, and does not significantly potentiate the effects of alcohol.The abuse potential of abecarnil is thought to be less than that of benzodiazepines, with only mild withdrawal symptoms noted after abrupt discontinuation of treatment.".
- Abecarnil atcPrefix "none".
- Abecarnil casNumber "111841-85-1".
- Abecarnil fdaUniiCode "IZM1PNJ3JL".
- Abecarnil iupacName "propan-2-yl 4-(methoxymethyl)-6-(phenylmethoxy) -9H-pyrido[5,4-b]indole-3-carboxylate".
- Abecarnil pubchem "65914".
- Abecarnil thumbnail Abecarnil.svg?width=300.
- Abecarnil wikiPageID "13385614".
- Abecarnil wikiPageRevisionID "633370270".
- Abecarnil atcPrefix "none".
- Abecarnil c "24".
- Abecarnil casNumber "111841".
- Abecarnil chembl "454095".
- Abecarnil chemspiderid "59323".
- Abecarnil eliminationHalfLife "25200.0".
- Abecarnil h "24".
- Abecarnil hasPhotoCollection Abecarnil.
- Abecarnil inchi "1".
- Abecarnil inchikey "RLFKILXOLJVUNF-UHFFFAOYAF".
- Abecarnil iupacName "propan-2-yl 4--6- -9H-pyrido[5,4-b]indole-3-carboxylate".
- Abecarnil kegg "D02594".
- Abecarnil molecularWeight "404.458".
- Abecarnil n "2".
- Abecarnil o "4".
- Abecarnil pubchem "65914".
- Abecarnil smiles "O=Cc4ncc3cc4COC".
- Abecarnil stdinchi "1".
- Abecarnil stdinchikey "RLFKILXOLJVUNF-UHFFFAOYSA-N".
- Abecarnil unii "IZM1PNJ3JL".
- Abecarnil verifiedfields "changed".
- Abecarnil verifiedrevid "477237117".
- Abecarnil subject Category:Anxiolytics.
- Abecarnil subject Category:Beta-Carbolines.
- Abecarnil subject Category:Carboxylate_esters.
- Abecarnil subject Category:Ethers.
- Abecarnil subject Category:GABAA_receptor_positive_allosteric_modulators.
- Abecarnil subject Category:Phenol_ethers.
- Abecarnil type Abstraction100002137.
- Abecarnil type CarboxylateEsters.
- Abecarnil type Chemical114806838.
- Abecarnil type Compound114818238.
- Abecarnil type Element114840755.
- Abecarnil type Ester114850483.
- Abecarnil type Ethers.
- Abecarnil type Material114580897.
- Abecarnil type Matter100020827.
- Abecarnil type OrganicCompound114727670.
- Abecarnil type Part113809207.
- Abecarnil type PhenolEthers.
- Abecarnil type PhysicalEntity100001930.
- Abecarnil type Quintessence114847103.
- Abecarnil type Relation100031921.
- Abecarnil type Substance100019613.
- Abecarnil type Drug.
- Abecarnil type DrugProduct.
- Abecarnil type Thing.
- Abecarnil type Q8386.
- Abecarnil comment "Abecarnil (ZK-112,119) is an anxiolytic drug from the β-Carboline family. It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures.".
- Abecarnil label "Abecarnil".
- Abecarnil sameAs m.03c3lrn.
- Abecarnil sameAs Q4666461.
- Abecarnil sameAs Q4666461.
- Abecarnil sameAs Abecarnil.
- Abecarnil wasDerivedFrom Abecarnil?oldid=633370270.
- Abecarnil depiction Abecarnil.svg.
- Abecarnil isPrimaryTopicOf Abecarnil.
