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- Q79453 subject Q6939141.
- Q79453 subject Q7145822.
- Q79453 subject Q7211399.
- Q79453 abstract "Immunoglobulin A (IgA, also referred to as sIgA) is an antibody that plays a critical role in immune function in the mucous membranes. More IgA is produced in mucosal linings than all other types of antibody combined; between three and five grams are secreted into the intestinal lumen each day. This accumulates up to 15% of the total immunoglobulin produced in the entire body.IgA has two subclasses (IgA1 and IgA2) and can exist in a dimeric form called secretory IgA (sIgA). In its secretory form, IgA is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes, thus sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions. sIgA can also inhibit inflammatory effects of other immunoglobulins. IgA is a poor activator of the complement system, and opsonises only weakly. Its heavy chains are of the type α.".
- Q79453 thumbnail Immunglobulin_A_as_Dimer.png?width=300.
- Q79453 wikiPageWikiLink Q101896.
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- Q79453 wikiPageWikiLink Q6939141.
- Q79453 wikiPageWikiLink Q7145822.
- Q79453 wikiPageWikiLink Q7211399.
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- Q79453 wikiPageWikiLink Q942926.
- Q79453 wikiPageWikiLink Q9625.
- Q79453 comment "Immunoglobulin A (IgA, also referred to as sIgA) is an antibody that plays a critical role in immune function in the mucous membranes. More IgA is produced in mucosal linings than all other types of antibody combined; between three and five grams are secreted into the intestinal lumen each day. This accumulates up to 15% of the total immunoglobulin produced in the entire body.IgA has two subclasses (IgA1 and IgA2) and can exist in a dimeric form called secretory IgA (sIgA).".
- Q79453 label "Immunoglobulin A".
- Q79453 depiction Immunglobulin_A_as_Dimer.png.