Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q7294620> ?p ?o }
Showing triples 1 to 38 of
38
with 100 triples per page.
- Q7294620 abstract "Ras-GRF1 is a guanine nucleotide exchange factor. Its function is to release guanosine diphosphate, GDP, from the signaling protein RAS, thus increasing the activity of RAS by allowing it to bind to guanosine triphosphate, GTP, returning it to its active state. In this way, Ras-GRF1 has a key role in regulating the RAS signaling pathway. Ras-GRF1 knockout mice have been shown to have learning and memory deficits associated with dysregulation of this pathway. Ras-GRF1 has also been shown to be upstream from IGF1, allowing it to control growth in mice. Although it is sometimes known as CDC25, it should not be confused with Cdc25. Ras-GRF1 is a paternally expressed imprinted gene, meaning that only the paternal allele of the gene is translated into protein. Disruption of this epigenetic imprinting also produces learning and memory deficits in neonatal mice.".
- Q7294620 arm "q".
- Q7294620 band "24".
- Q7294620 chromosome "15".
- Q7294620 entrezgene "5923".
- Q7294620 hgncid "9875".
- Q7294620 omim "606600".
- Q7294620 refseq "NM_153815".
- Q7294620 symbol "GRF1".
- Q7294620 symbol "RASGRF1".
- Q7294620 uniprot "Q13972".
- Q7294620 wikiPageWikiLink Q14863714.
- Q7294620 wikiPageWikiLink Q3775177.
- Q7294620 wikiPageWikiLink Q392227.
- Q7294620 wikiPageWikiLink Q422582.
- Q7294620 wikiPageWikiLink Q424396.
- Q7294620 wikiPageWikiLink Q80726.
- Q7294620 wikiPageWikiLink Q84087.
- Q7294620 wikiPageWikiLink Q901088.
- Q7294620 altsymbols "GRF1".
- Q7294620 arm "q".
- Q7294620 band "24".
- Q7294620 chromosome "15".
- Q7294620 entrezgene "5923".
- Q7294620 hgncid "9875".
- Q7294620 name "Ras protein-specific guanine nucleotide-releasing factor 1".
- Q7294620 omim "606600".
- Q7294620 refseq "NM_153815".
- Q7294620 symbol "RASGRF1".
- Q7294620 uniprot "Q13972".
- Q7294620 type Biomolecule.
- Q7294620 type Protein.
- Q7294620 type Thing.
- Q7294620 type Q206229.
- Q7294620 type Q8054.
- Q7294620 comment "Ras-GRF1 is a guanine nucleotide exchange factor. Its function is to release guanosine diphosphate, GDP, from the signaling protein RAS, thus increasing the activity of RAS by allowing it to bind to guanosine triphosphate, GTP, returning it to its active state. In this way, Ras-GRF1 has a key role in regulating the RAS signaling pathway. Ras-GRF1 knockout mice have been shown to have learning and memory deficits associated with dysregulation of this pathway.".
- Q7294620 label "Ras-GRF1".
- Q7294620 name "Ras protein-specific guanine nucleotide-releasing factor 1".