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- Q7120082 subject Q52359.
- Q7120082 subject Q8802906.
- Q7120082 subject Q8919936.
- Q7120082 subject Q9601368.
- Q7120082 abstract "PP2 is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases. It strongly inhibits the kinases Lck (IC50=4 nM), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 µM) and JAK2 (50 µM). Despite its extensive use as a Src-selective inhibitor, recent research has shown that PP2 is non-selective and inhibits many other kinases with similar affinities.".
- Q7120082 iupacName "4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine".
- Q7120082 thumbnail PP2_skeletal.svg?width=300.
- Q7120082 wikiPageWikiLink Q14865565.
- Q7120082 wikiPageWikiLink Q14885202.
- Q7120082 wikiPageWikiLink Q14907110.
- Q7120082 wikiPageWikiLink Q14914514.
- Q7120082 wikiPageWikiLink Q18024903.
- Q7120082 wikiPageWikiLink Q18026836.
- Q7120082 wikiPageWikiLink Q286779.
- Q7120082 wikiPageWikiLink Q407927.
- Q7120082 wikiPageWikiLink Q52359.
- Q7120082 wikiPageWikiLink Q672821.
- Q7120082 wikiPageWikiLink Q7251487.
- Q7120082 wikiPageWikiLink Q7582406.
- Q7120082 wikiPageWikiLink Q8802906.
- Q7120082 wikiPageWikiLink Q8919936.
- Q7120082 wikiPageWikiLink Q9601368.
- Q7120082 iupacname "4".
- Q7120082 type ChemicalCompound.
- Q7120082 type ChemicalSubstance.
- Q7120082 type ChemicalObject.
- Q7120082 type Thing.
- Q7120082 type Q11173.
- Q7120082 comment "PP2 is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases. It strongly inhibits the kinases Lck (IC50=4 nM), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 µM) and JAK2 (50 µM). Despite its extensive use as a Src-selective inhibitor, recent research has shown that PP2 is non-selective and inhibits many other kinases with similar affinities.".
- Q7120082 label "PP2 (kinase inhibitor)".
- Q7120082 depiction PP2_skeletal.svg.