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- Q6815109 subject Q8395796.
- Q6815109 abstract "Membrane-bound transcription factor site-2 protease, or site-2 protease (S2P) for short, is an enzyme (EC 3.4.24.85) encoded by the MBTPS2 gene which liberates the N-terminal fragment of sterol regulatory element-binding protein (SREBP) transcription factors from membranes. S2P cleaves the transmembrane domain of SREPB, making it a member of the class of intramembrane proteases.S2P endopeptidase (EC 3.4.24.85) is an enzyme. This enzyme catalyses the following chemical reaction Cleaves several transcription factors that are type-2 transmembrane proteins within membrane-spanning domains. Known substrates include sterol regulatory element-binding protein (SREBP)-1, SREBP-2 and forms of the transcriptional activator ATF6. This enzyme belongs to the peptidase family M50.".
- Q6815109 arm "p".
- Q6815109 band "22.1".
- Q6815109 chromosome "X".
- Q6815109 ecNumber "3.4.24.85".
- Q6815109 entrezgene "51360".
- Q6815109 hgncid "15455".
- Q6815109 locusSupplementaryData "-p22.2".
- Q6815109 omim "300294".
- Q6815109 refseq "NM_015884".
- Q6815109 symbol "MBTPS2".
- Q6815109 symbol "S2P".
- Q6815109 uniprot "O43462".
- Q6815109 wikiPageWikiLink Q174576.
- Q6815109 wikiPageWikiLink Q36534.
- Q6815109 wikiPageWikiLink Q407384.
- Q6815109 wikiPageWikiLink Q416064.
- Q6815109 wikiPageWikiLink Q424204.
- Q6815109 wikiPageWikiLink Q6058452.
- Q6815109 wikiPageWikiLink Q7187.
- Q6815109 wikiPageWikiLink Q7834587.
- Q6815109 wikiPageWikiLink Q8047.
- Q6815109 wikiPageWikiLink Q82264.
- Q6815109 wikiPageWikiLink Q8395796.
- Q6815109 wikiPageWikiLink Q905792.
- Q6815109 altsymbols "S2P".
- Q6815109 arm "p".
- Q6815109 band "22.1".
- Q6815109 chromosome "X".
- Q6815109 ecNumber "3.4".
- Q6815109 ecnumber "3.4".
- Q6815109 entrezgene "51360".
- Q6815109 hgncid "15455".
- Q6815109 locussupplementarydata "-p22.2".
- Q6815109 name "S2P endopeptidase".
- Q6815109 name "membrane-bound transcription factor peptidase, site 2".
- Q6815109 omim "300294".
- Q6815109 refseq "NM_015884".
- Q6815109 symbol "MBTPS2".
- Q6815109 uniprot "O43462".
- Q6815109 type Biomolecule.
- Q6815109 type Protein.
- Q6815109 type Thing.
- Q6815109 type Q206229.
- Q6815109 type Q8054.
- Q6815109 comment "Membrane-bound transcription factor site-2 protease, or site-2 protease (S2P) for short, is an enzyme (EC 3.4.24.85) encoded by the MBTPS2 gene which liberates the N-terminal fragment of sterol regulatory element-binding protein (SREBP) transcription factors from membranes. S2P cleaves the transmembrane domain of SREPB, making it a member of the class of intramembrane proteases.S2P endopeptidase (EC 3.4.24.85) is an enzyme.".
- Q6815109 label "Membrane-bound transcription factor site-2 protease".
- Q6815109 name "membrane-bound transcription factor peptidase, site 2".