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- Q652676 subject Q8390757.
- Q652676 abstract "Opioid replacement therapy (ORT) (also called opioid substitution therapy (OST) or opioid maintenance therapy) is a medical treatment that involves replacing an illegal opioid, such as heroin, with a longer acting but less euphoric opioid; methadone or buprenorphine are typically used and the drug is taken under medical supervision. The goal of the therapy is to reduce health risks for the consumer, reducing criminal behaviour and improving the long-term physical and psychological condition of the patient. Most strategies aim ultimately to reduce drug use and lead to abstinence, but often do not make this a condition. Some formulations of buprenorphine incorporate the opiate antagonist naloxone during the production of the pill form to prevent people from crushing the tablets and injecting them, instead of using the sublingual (under the tongue) route of administration.In some countries, such as Switzerland, Austria, and Slovenia, patients may be treated with slow-release morphine or pure heroin (in the case of Switzerland) when methadone is deemed inappropriate due to the individual's circumstances. In Switzerland, the prescription of medicinal heroin started in 1994 and has since proven to be effective in combating the negative consequences of drug use. Usually, only a small percentage of patients receive heroin and have to fulfil a number of criteria. In Germany, dihydrocodeine has been used off-label in ORT for many years, however it is no longer frequently prescribed for this purpose. Research into the usefulness of piritramide, extended-release hydromorphone (including polymer implants lasting up to 90 days), dihydroetorphine and other drugs for ORT is at various stages in a number of countries.".
- Q652676 thumbnail US_timeline._Prescription_opioid_pain_reliever_deaths.jpg?width=300.
- Q652676 wikiPageWikiLink Q1105202.
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- Q652676 wikiPageWikiLink Q215.
- Q652676 wikiPageWikiLink Q282902.
- Q652676 wikiPageWikiLink Q303646.
- Q652676 wikiPageWikiLink Q317309.
- Q652676 wikiPageWikiLink Q3268188.
- Q652676 wikiPageWikiLink Q377270.
- Q652676 wikiPageWikiLink Q39.
- Q652676 wikiPageWikiLink Q391682.
- Q652676 wikiPageWikiLink Q40.
- Q652676 wikiPageWikiLink Q407721.
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- Q652676 wikiPageWikiLink Q498902.
- Q652676 wikiPageWikiLink Q5743362.
- Q652676 wikiPageWikiLink Q588982.
- Q652676 wikiPageWikiLink Q60168.
- Q652676 wikiPageWikiLink Q636107.
- Q652676 wikiPageWikiLink Q6718023.
- Q652676 wikiPageWikiLink Q7817.
- Q652676 wikiPageWikiLink Q784720.
- Q652676 wikiPageWikiLink Q8390757.
- Q652676 wikiPageWikiLink Q841236.
- Q652676 comment "Opioid replacement therapy (ORT) (also called opioid substitution therapy (OST) or opioid maintenance therapy) is a medical treatment that involves replacing an illegal opioid, such as heroin, with a longer acting but less euphoric opioid; methadone or buprenorphine are typically used and the drug is taken under medical supervision.".
- Q652676 label "Opioid replacement therapy".
- Q652676 depiction US_timeline._Prescription_opioid_pain_reliever_deaths.jpg.