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- Q5897962 subject Q7348588.
- Q5897962 subject Q8802898.
- Q5897962 subject Q9089708.
- Q5897962 abstract "HOOK is a family of evolutionarily related proteins.This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organisms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved N-terminal domain mediates attachment to microtubules, whereas the central coiled coil motif mediates homodimerisation and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localised to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head.".
- Q5897962 symbol "HOOK".
- Q5897962 wikiPageWikiLink Q18039690.
- Q5897962 wikiPageWikiLink Q18040241.
- Q5897962 wikiPageWikiLink Q18047590.
- Q5897962 wikiPageWikiLink Q284398.
- Q5897962 wikiPageWikiLink Q310425.
- Q5897962 wikiPageWikiLink Q417841.
- Q5897962 wikiPageWikiLink Q45948.
- Q5897962 wikiPageWikiLink Q7348588.
- Q5897962 wikiPageWikiLink Q8802898.
- Q5897962 wikiPageWikiLink Q903650.
- Q5897962 wikiPageWikiLink Q9089708.
- Q5897962 symbol "HOOK".
- Q5897962 type Biomolecule.
- Q5897962 type Protein.
- Q5897962 type Thing.
- Q5897962 type Q206229.
- Q5897962 type Q8054.
- Q5897962 comment "HOOK is a family of evolutionarily related proteins.This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organisms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3.".
- Q5897962 label "Hook protein".