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- Q5731724 subject Q10195735.
- Q5731724 subject Q15259633.
- Q5731724 subject Q8550336.
- Q5731724 abstract "The Hepatitis C virus internal ribosome entry site, or HCV IRES, is an RNA structure within the 5'UTR of the HCV genome that mediates cap-independent translation initiation.Protein translation of most eukaryotic mRNAs occurs by a cap-dependent mechanism and requires association of Met-tRNAiMet, several eukaryotic initiation factors, and GTP with the 40S ribosomal subunit, recruitment to the 5' cap, and scanning along the 5' UTR to reach to start codon. In contrast, translation of hepatitis C virus (HCV) mRNA is initiated by a different mechanism from the usual 5' cap-binding model. This alternate mechanism relies on the direct binding of the 40S ribosomal subunit by the internal ribosome entry site (IRES) in the 5' UTR of HCV RNA. The HCV IRES adopts a complex structure, and may differ significantly from IRES elements identified in picornaviruses. A small number of eukaryotic mRNA have been shown to be translated by internal ribosome entry.".
- Q5731724 thumbnail RF00061.jpg?width=300.
- Q5731724 wikiPageWikiLink Q1017133.
- Q5731724 wikiPageWikiLink Q10195735.
- Q5731724 wikiPageWikiLink Q1093165.
- Q5731724 wikiPageWikiLink Q11053.
- Q5731724 wikiPageWikiLink Q15259633.
- Q5731724 wikiPageWikiLink Q15712714.
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- Q5731724 wikiPageWikiLink Q17916047.
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- Q5731724 wikiPageWikiLink Q5408696.
- Q5731724 wikiPageWikiLink Q7020.
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- Q5731724 wikiPageWikiLink Q7191061.
- Q5731724 wikiPageWikiLink Q7249510.
- Q5731724 wikiPageWikiLink Q808.
- Q5731724 wikiPageWikiLink Q8550336.
- Q5731724 wikiPageWikiLink Q906570.
- Q5731724 wikiPageWikiLink Q936600.
- Q5731724 wikiPageWikiLink Q937624.
- Q5731724 comment "The Hepatitis C virus internal ribosome entry site, or HCV IRES, is an RNA structure within the 5'UTR of the HCV genome that mediates cap-independent translation initiation.Protein translation of most eukaryotic mRNAs occurs by a cap-dependent mechanism and requires association of Met-tRNAiMet, several eukaryotic initiation factors, and GTP with the 40S ribosomal subunit, recruitment to the 5' cap, and scanning along the 5' UTR to reach to start codon.".
- Q5731724 label "Hepatitis C virus internal ribosome entry site".
- Q5731724 depiction RF00061.jpg.