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- Q5383794 subject Q8255962.
- Q5383794 subject Q8421769.
- Q5383794 subject Q8501360.
- Q5383794 subject Q8639167.
- Q5383794 abstract "Epoetin alfa (rINN) /ɛˈpoʊ.ᵻtᵻn/ is human erythropoietin produced in cell culture using recombinant DNA technology. Authorised by the European Medicines Agency on 28 August 2007, it stimulates erythropoiesis (increases red blood cell levels) and is used to treat anemia, commonly associated with chronic renal failure and cancer chemotherapy. Epoetin is manufactured by Amgen and is marketed by Amgen under the trade names Epogen and by Johnson & Johnson's subsidiary, Janseen Biotech, formerly Ortho Biotech Products, LP, as Procrit, pursuant to a Product License Agreement. Epogen and Procrit are the same drug. Its annual cost to U.S. patients was $8,447 per patient per year in 2009. Darbepoetin alfa (rINN) /dɑrbəˈpɔɪtɨn/ is a glycosylation analog of erythropoietin containing 2 additional N-linked carbohydrate chains, also manufactured by Amgen. Darbepoetin is marketed by Amgen under the trade name Aranesp. The FDA warnings and safety precautions for Procrit, Epogen and Aransep are identical.For several years, epoetin alfa has been the single greatest drug expenditure paid for by U.S. Medicare. In 2010, Medicare paid $2 billion. Dosing is controversial, and higher doses, to raise hematocrit to normal levels, are associated with higher risks of hospitalization, strokes and death.".
- Q5383794 atcPrefix "B03".
- Q5383794 atcSuffix "XA01".
- Q5383794 casNumber "113427-24-0".
- Q5383794 drugbank "DB00016".
- Q5383794 fdaUniiCode "64FS3BFH5W".
- Q5383794 wikiPageExternalLink epogen_piu_pt_english.pdf.
- Q5383794 wikiPageExternalLink article.htm.
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- Q5383794 atcPrefix "B03".
- Q5383794 atcSuffix "XA01".
- Q5383794 casNumber "113427".
- Q5383794 drugbank "DB00016".
- Q5383794 unii "64".
- Q5383794 type ChemicalSubstance.
- Q5383794 type Drug.
- Q5383794 type ChemicalObject.
- Q5383794 type Thing.
- Q5383794 type Q8386.
- Q5383794 comment "Epoetin alfa (rINN) /ɛˈpoʊ.ᵻtᵻn/ is human erythropoietin produced in cell culture using recombinant DNA technology. Authorised by the European Medicines Agency on 28 August 2007, it stimulates erythropoiesis (increases red blood cell levels) and is used to treat anemia, commonly associated with chronic renal failure and cancer chemotherapy.".
- Q5383794 label "Epoetin alfa".