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- Q5275424 subject Q6853449.
- Q5275424 abstract "Diffuse proliferative nephritis (DPN) or glomerulonephritis (DPGN) is a type of glomerulonephritis that is the most serious form of renal lesions in SLE and is also the most common, occurring in 35% to 60% of patients. Most of the glomeruli show endothelial and mesangial proliferation affecting the entire glomerulus, leading to diffuse hypercellularity of the glomeruli, producing in some cases epithelial crescents that fill Bowman's space. When extensive, immune complexes create an overall thickening of the capillary wall, resembling rigid "wire loops" on routine light microscopy. Electron microscopy reveals electron-dense subendothelial immune complexes (between endothelium and basement membrane). Immune complexes can be visualized by staining with fluorescent antibodies directed against immunoglobulins or complement, resulting in a granular fluorescent staining pattern. In due course, glomerular injury gives rise to scarring (glomerulosclerosis). Most of these patients have hematuria with moderate to severe proteinuria, hypertension, and renal insufficiency.".
- Q5275424 wikiPageWikiLink Q1066345.
- Q5275424 wikiPageWikiLink Q1074953.
- Q5275424 wikiPageWikiLink Q111140.
- Q5275424 wikiPageWikiLink Q1182592.
- Q5275424 wikiPageWikiLink Q1246948.
- Q5275424 wikiPageWikiLink Q132560.
- Q5275424 wikiPageWikiLink Q1509367.
- Q5275424 wikiPageWikiLink Q1515072.
- Q5275424 wikiPageWikiLink Q163214.
- Q5275424 wikiPageWikiLink Q189159.
- Q5275424 wikiPageWikiLink Q191807.
- Q5275424 wikiPageWikiLink Q206060.
- Q5275424 wikiPageWikiLink Q334848.
- Q5275424 wikiPageWikiLink Q350559.
- Q5275424 wikiPageWikiLink Q373597.
- Q5275424 wikiPageWikiLink Q41301.
- Q5275424 wikiPageWikiLink Q41861.
- Q5275424 wikiPageWikiLink Q476921.
- Q5275424 wikiPageWikiLink Q5571239.
- Q5275424 wikiPageWikiLink Q570197.
- Q5275424 wikiPageWikiLink Q575241.
- Q5275424 wikiPageWikiLink Q605006.
- Q5275424 wikiPageWikiLink Q6853449.
- Q5275424 wikiPageWikiLink Q79460.
- Q5275424 comment "Diffuse proliferative nephritis (DPN) or glomerulonephritis (DPGN) is a type of glomerulonephritis that is the most serious form of renal lesions in SLE and is also the most common, occurring in 35% to 60% of patients. Most of the glomeruli show endothelial and mesangial proliferation affecting the entire glomerulus, leading to diffuse hypercellularity of the glomeruli, producing in some cases epithelial crescents that fill Bowman's space.".
- Q5275424 label "Diffuse proliferative nephritis".