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- Q5198706 subject Q7240335.
- Q5198706 subject Q8256351.
- Q5198706 subject Q8872474.
- Q5198706 subject Q8919936.
- Q5198706 abstract "Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in vivo has been thought to be primarily responsible for the antimalarial activity of proguanil. However, more recent work has indicated that, while proguanil is synergistic with the drug atovaquone (as in the combination Malarone), cycloguanil is in fact antagonistic to the effects of atovaquone, suggesting that, unlike cycloguanil, proguanil may have an alternative mechanism of antimalarial action besides dihydrofolate reductase inhibition.Although cycloguanil is not currently in general use as an antimalarial, the continuing development of resistance to current antimalarial drugs has led to renewed interest in studying the use of cycloguanil in combination with other drugs.".
- Q5198706 atcPrefix "P01".
- Q5198706 atcSuffix "BB02".
- Q5198706 casNumber "516-21-2".
- Q5198706 fdaUniiCode "26RM326WVN".
- Q5198706 iupacName "1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine".
- Q5198706 pubchem "9049".
- Q5198706 thumbnail Cycloguanil.svg?width=300.
- Q5198706 wikiPageWikiLink Q418179.
- Q5198706 wikiPageWikiLink Q420607.
- Q5198706 wikiPageWikiLink Q521616.
- Q5198706 wikiPageWikiLink Q5276427.
- Q5198706 wikiPageWikiLink Q7240335.
- Q5198706 wikiPageWikiLink Q757702.
- Q5198706 wikiPageWikiLink Q8256351.
- Q5198706 wikiPageWikiLink Q8872474.
- Q5198706 wikiPageWikiLink Q8919936.
- Q5198706 atcPrefix "P01".
- Q5198706 atcSuffix "BB02".
- Q5198706 casNumber "516".
- Q5198706 iupacName "1".
- Q5198706 pubchem "9049".
- Q5198706 unii "26".
- Q5198706 type ChemicalSubstance.
- Q5198706 type Drug.
- Q5198706 type ChemicalObject.
- Q5198706 type Thing.
- Q5198706 type Q8386.
- Q5198706 comment "Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in vivo has been thought to be primarily responsible for the antimalarial activity of proguanil.".
- Q5198706 label "Cycloguanil".
- Q5198706 depiction Cycloguanil.svg.