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- Q5156356 subject Q8760220.
- Q5156356 abstract "A competitive antagonist is a receptor antagonist that binds to a receptor but does not activate the receptor. The antagonist will compete with available agonist for receptor binding sites on the same receptor. Sufficient antagonist will displace the agonist from the binding sites, resulting in a lower frequency of receptor activation.Presence of a competitive antagonist will shift an agonism dose-response curve to the right. A Schild plot for a competitive antagonist will have a slope equal to 1, and the X-intercept and Y-intercept will each equal the dissociation constant of the antagonist.Competitive antagonists are used to prevent the activity of drugs, and to reverse the effects of drugs that have already been consumed. Naloxone (also known as Narcan) is used to reverse opioid overdose caused by drugs such as heroin or morphine. Similarly, Ro15-4513 is an antidote to alcohol and flumazenil is an antidote to benzodiazepines.A competitive antagonist can be reversible competitive antagonist or irreversible competitive antagonist.".
- Q5156356 wikiPageWikiLink Q1251001.
- Q5156356 wikiPageWikiLink Q17154378.
- Q5156356 wikiPageWikiLink Q208467.
- Q5156356 wikiPageWikiLink Q2235423.
- Q5156356 wikiPageWikiLink Q282902.
- Q5156356 wikiPageWikiLink Q389934.
- Q5156356 wikiPageWikiLink Q410943.
- Q5156356 wikiPageWikiLink Q421920.
- Q5156356 wikiPageWikiLink Q60168.
- Q5156356 wikiPageWikiLink Q616005.
- Q5156356 wikiPageWikiLink Q7339199.
- Q5156356 wikiPageWikiLink Q81225.
- Q5156356 wikiPageWikiLink Q83871.
- Q5156356 wikiPageWikiLink Q8760220.
- Q5156356 wikiPageWikiLink Q898254.
- Q5156356 comment "A competitive antagonist is a receptor antagonist that binds to a receptor but does not activate the receptor. The antagonist will compete with available agonist for receptor binding sites on the same receptor. Sufficient antagonist will displace the agonist from the binding sites, resulting in a lower frequency of receptor activation.Presence of a competitive antagonist will shift an agonism dose-response curve to the right.".
- Q5156356 label "Competitive antagonist".