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- Q5063037 subject Q7165066.
- Q5063037 abstract "Centrosomes are the major microtubule organizing center (MTOC) in mammalian cells. Failure of centrosome regulation can cause mistakes in chromosome segregation and is associated with aneuploidy. A centrosome is composed of two orthogonal cylindrical proteins, called centrioles, which are surrounded by an electron dense and protein dense amorphous cloud of pericentriolar matrix, often abbreviated as "PCM". The PCM is essential for nucleation and organization of microtubules. The centrosome cycle is important to ensure that daughter cells receive a centrosome after cell division. As the cell cycle progresses, the centrosome undergoes a series of morphological and functional changes. Initiation of the centrosome cycle occurs early in the cell cycle, so that by the time mitosis occurs there are two centrosomes.The centrosome cycle consists of four phases that are synchronized to cell cycle. These include: centrosome duplication during the G1 phase and S Phase, centrosome maturation in the G2 phase, centrosome separation in the mitotic phase, and centrosome disorientation in the late mitotic phase—G1 phase.".
- Q5063037 thumbnail Centrosome_Cycle.svg?width=300.
- Q5063037 wikiPageWikiLink Q130996.
- Q5063037 wikiPageWikiLink Q133226.
- Q5063037 wikiPageWikiLink Q14763023.
- Q5063037 wikiPageWikiLink Q14818098.
- Q5063037 wikiPageWikiLink Q14911732.
- Q5063037 wikiPageWikiLink Q178355.
- Q5063037 wikiPageWikiLink Q18028978.
- Q5063037 wikiPageWikiLink Q18030194.
- Q5063037 wikiPageWikiLink Q18034631.
- Q5063037 wikiPageWikiLink Q18052579.
- Q5063037 wikiPageWikiLink Q188909.
- Q5063037 wikiPageWikiLink Q188941.
- Q5063037 wikiPageWikiLink Q190769.
- Q5063037 wikiPageWikiLink Q215067.
- Q5063037 wikiPageWikiLink Q22299157.
- Q5063037 wikiPageWikiLink Q227339.
- Q5063037 wikiPageWikiLink Q2289513.
- Q5063037 wikiPageWikiLink Q242736.
- Q5063037 wikiPageWikiLink Q2889948.
- Q5063037 wikiPageWikiLink Q306379.
- Q5063037 wikiPageWikiLink Q306383.
- Q5063037 wikiPageWikiLink Q333666.
- Q5063037 wikiPageWikiLink Q5198260.
- Q5063037 wikiPageWikiLink Q5198274.
- Q5063037 wikiPageWikiLink Q529622.
- Q5063037 wikiPageWikiLink Q7165066.
- Q5063037 wikiPageWikiLink Q7168391.
- Q5063037 wikiPageWikiLink Q7225885.
- Q5063037 wikiPageWikiLink Q7247205.
- Q5063037 wikiPageWikiLink Q777359.
- Q5063037 wikiPageWikiLink Q903644.
- Q5063037 comment "Centrosomes are the major microtubule organizing center (MTOC) in mammalian cells. Failure of centrosome regulation can cause mistakes in chromosome segregation and is associated with aneuploidy. A centrosome is composed of two orthogonal cylindrical proteins, called centrioles, which are surrounded by an electron dense and protein dense amorphous cloud of pericentriolar matrix, often abbreviated as "PCM". The PCM is essential for nucleation and organization of microtubules.".
- Q5063037 label "Centrosome cycle".
- Q5063037 depiction Centrosome_Cycle.svg.