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- Q4681115 subject Q7066228.
- Q4681115 abstract "Addiction modules are toxin-antitoxin systems. Each consists of a pair of genes that specify two components: a stable toxin and an unstable antitoxin that interferes with the lethal action of the toxin. Found first in E. coli on low copy number plasmids, addiction modules are responsible for a process called the postsegregational killing effect. When bacteria lose these plasmid(s) (or other extrachromosomal elements), the cured cells are selectively killed because the unstable antitoxin is degraded faster than the more stable toxin. The term "addiction" is used because the cell depends on the de novo synthesis of the antitoxin for cell survival. Thus, addiction modules are implicated in maintaining the stability of extrachromosomal elements.".
- Q4681115 thumbnail CcdAB_Toxin-Antitoxin_System.png?width=300.
- Q4681115 wikiPageExternalLink annurev.micro.53.1.43.
- Q4681115 wikiPageExternalLink 1528.pdf.
- Q4681115 wikiPageExternalLink ncb836.html.
- Q4681115 wikiPageWikiLink Q1063702.
- Q4681115 wikiPageWikiLink Q10876.
- Q4681115 wikiPageWikiLink Q139677.
- Q4681115 wikiPageWikiLink Q16948788.
- Q4681115 wikiPageWikiLink Q172778.
- Q4681115 wikiPageWikiLink Q212410.
- Q4681115 wikiPageWikiLink Q224093.
- Q4681115 wikiPageWikiLink Q25419.
- Q4681115 wikiPageWikiLink Q3495384.
- Q4681115 wikiPageWikiLink Q3962231.
- Q4681115 wikiPageWikiLink Q5422184.
- Q4681115 wikiPageWikiLink Q7066228.
- Q4681115 wikiPageWikiLink Q7187.
- Q4681115 wikiPageWikiLink Q7201810.
- Q4681115 wikiPageWikiLink Q7868.
- Q4681115 wikiPageWikiLink Q908550.
- Q4681115 comment "Addiction modules are toxin-antitoxin systems. Each consists of a pair of genes that specify two components: a stable toxin and an unstable antitoxin that interferes with the lethal action of the toxin. Found first in E. coli on low copy number plasmids, addiction modules are responsible for a process called the postsegregational killing effect.".
- Q4681115 label "Addiction module".
- Q4681115 depiction CcdAB_Toxin-Antitoxin_System.png.
