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- Q425402 subject Q8395793.
- Q425402 subject Q8395796.
- Q425402 subject Q8802898.
- Q425402 abstract "A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal. An example of this would be meltrin which plays a significant role in the fusion of muscle cells during embryo development, in a process known as myogenesis.Most metalloproteases require zinc, but some use cobalt. The metal ion is coordinated to the protein via three ligands. The ligands co-ordinating the metal ion can vary with histidine, glutamate, aspartate, lysine, and arginine. The fourth coordination position is taken up by a labile water molecule.Treatment with chelating agents such as EDTA leads to complete inactivation. EDTA is a metal chelator that removes zinc, which is essential for activity. They are also inhibited by the chelator orthophenanthroline.".
- Q425402 symbol "Peptidase_M48".
- Q425402 symbol "Peptidase_M50".
- Q425402 wikiPageExternalLink M.
- Q425402 wikiPageExternalLink Metalloproteases.
- Q425402 wikiPageWikiLink Q11369.
- Q425402 wikiPageWikiLink Q11426.
- Q425402 wikiPageWikiLink Q15712714.
- Q425402 wikiPageWikiLink Q173670.
- Q425402 wikiPageWikiLink Q1757382.
- Q425402 wikiPageWikiLink Q177332.
- Q425402 wikiPageWikiLink Q178430.
- Q425402 wikiPageWikiLink Q178450.
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- Q425402 wikiPageWikiLink Q8047.
- Q425402 wikiPageWikiLink Q8054.
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- Q425402 wikiPageWikiLink Q82264.
- Q425402 wikiPageWikiLink Q8395793.
- Q425402 wikiPageWikiLink Q8395796.
- Q425402 wikiPageWikiLink Q8802898.
- Q425402 wikiPageWikiLink Q901612.
- Q425402 wikiPageWikiLink Q903495.
- Q425402 symbol "Peptidase_M48".
- Q425402 symbol "Peptidase_M50".
- Q425402 type Biomolecule.
- Q425402 type Protein.
- Q425402 type Thing.
- Q425402 type Q206229.
- Q425402 type Q8054.
- Q425402 comment "A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal. An example of this would be meltrin which plays a significant role in the fusion of muscle cells during embryo development, in a process known as myogenesis.Most metalloproteases require zinc, but some use cobalt. The metal ion is coordinated to the protein via three ligands. The ligands co-ordinating the metal ion can vary with histidine, glutamate, aspartate, lysine, and arginine.".
- Q425402 label "Metalloproteinase".