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- Q425157 subject Q11390205.
- Q425157 subject Q7071513.
- Q425157 subject Q8879724.
- Q425157 abstract "Linamarin is a cyanogenic glucoside found in the leaves and roots of plants such as cassava, lima beans, and flax. It is a glucoside of acetone cyanohydrin. Upon exposure to enzymes and gut flora in the human intestine, linamarin and its methylated relative lotaustralin can decompose to the toxic chemical hydrogen cyanide; hence food uses of plants that contain significant quantities of linamarin require extensive preparation and detoxification. Ingested and absorbed linamarin is rapidly excreted in the urine and the glucoside itself does not appear to be acutely toxic. Consumption of cassava products with low levels of linamarin is widespread in the low-land tropics. Ingestion of food prepared from insufficiently processed cassava roots with high linamarin levels has been associated with dietary toxicity, particularly with the upper motor neuron disease known as konzo to the African populations in which it was first described by Trolli and later through the research network initiated by Hans Rosling. However, the toxicity is believed to be induced by ingestion of acetone cyanohydrin, the breakdown product of linamarin. Dietary exposure to linamarin has also been reported as a risk factor in developing glucose intolerance and diabetes, although studies in experimental animals have been inconsistent in reproducing this effect and may indicate that the primary effect is in aggravating existing conditions rather than inducing diabetes on its own.The generation of cyanide from linamarin is usually enzymatic and occurs when linamarin is exposed to linamarase, an enzyme normally expressed in the cell walls of cassava plants. Because the resulting cyanide derivatives are volatile, processing methods that induce such exposure are common traditional means of cassava preparation; foodstuffs are usually made from cassava after extended blanching, boiling, or fermentation. Food products made from cassava plants include garri (toasted cassava tubers), porridge-like fufu, the dough agbelima, and cassava flour.Recent research efforts have developed a transgenic cassava plant that stably downregulates linamarin production via RNA interference.".
- Q425157 iupacName "(hydroxymethyl)oxan-2-yl]oxy-propanenitrile".
- Q425157 iupacName "2-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-".
- Q425157 thumbnail Linamarin.svg?width=300.
- Q425157 wikiPageWikiLink Q11390205.
- Q425157 wikiPageWikiLink Q1166136.
- Q425157 wikiPageWikiLink Q12206.
- Q425157 wikiPageWikiLink Q1275814.
- Q425157 wikiPageWikiLink Q128700.
- Q425157 wikiPageWikiLink Q137173.
- Q425157 wikiPageWikiLink Q1494252.
- Q425157 wikiPageWikiLink Q183319.
- Q425157 wikiPageWikiLink Q185076.
- Q425157 wikiPageWikiLink Q201993.
- Q425157 wikiPageWikiLink Q222936.
- Q425157 wikiPageWikiLink Q26075.
- Q425157 wikiPageWikiLink Q2661464.
- Q425157 wikiPageWikiLink Q3183734.
- Q425157 wikiPageWikiLink Q36465.
- Q425157 wikiPageWikiLink Q38344.
- Q425157 wikiPageWikiLink Q3875059.
- Q425157 wikiPageWikiLink Q41716.
- Q425157 wikiPageWikiLink Q4407.
- Q425157 wikiPageWikiLink Q45108.
- Q425157 wikiPageWikiLink Q506763.
- Q425157 wikiPageWikiLink Q588259.
- Q425157 wikiPageWikiLink Q6431240.
- Q425157 wikiPageWikiLink Q6550240.
- Q425157 wikiPageWikiLink Q6950796.
- Q425157 wikiPageWikiLink Q7071513.
- Q425157 wikiPageWikiLink Q739734.
- Q425157 wikiPageWikiLink Q8047.
- Q425157 wikiPageWikiLink Q83124.
- Q425157 wikiPageWikiLink Q8879724.
- Q425157 wikiPageWikiLink Q905492.
- Q425157 wikiPageWikiLink Q941004.
- Q425157 iupacname "2".
- Q425157 iupacname "oxan-2-yl]oxy-propanenitrile".
- Q425157 type ChemicalCompound.
- Q425157 type ChemicalSubstance.
- Q425157 type ChemicalObject.
- Q425157 type Thing.
- Q425157 type Q11173.
- Q425157 comment "Linamarin is a cyanogenic glucoside found in the leaves and roots of plants such as cassava, lima beans, and flax. It is a glucoside of acetone cyanohydrin. Upon exposure to enzymes and gut flora in the human intestine, linamarin and its methylated relative lotaustralin can decompose to the toxic chemical hydrogen cyanide; hence food uses of plants that contain significant quantities of linamarin require extensive preparation and detoxification.".
- Q425157 label "Linamarin".
- Q425157 depiction Linamarin.svg.