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- Q423787 subject Q15252755.
- Q423787 subject Q7214382.
- Q423787 subject Q7215865.
- Q423787 subject Q7369691.
- Q423787 subject Q8264664.
- Q423787 subject Q8412954.
- Q423787 abstract "Piperacillin is a broad-spectrum β-lactam antibiotic of the ureidopenicillin class. The chemical structure of piperacillin and other ureidopenicillins incorporates a polar side chain that enhances penetration into Gram-(-) bacteria and reduces susceptibility to cleavage by Gram-(-) beta lactamase enzymes. These properties confer activity against the important hospital pathogen Pseudomonas aeruginosa. Thus piperacillin is sometimes referred to as an "anti-pseudomonal penicillin".When used alone, piperacillin lacks strong activity against the Gram positive pathogen Staphylococcus aureus, as the beta-lactam ring is broken by the bacteria's beta-lactamase.Piperacillin is most commonly used in combination with the beta-lactamase inhibitor tazobactam (piperacillin/tazobactam) (tradename "Zosyn"), which enhances piperacillin's effectiveness by inhibiting many beta lactamases to which it is susceptible. The co-administration of tazobactam does not confer activity against methicillin-resistant Staphylococcus aureus, however, as penicillins (and most other beta lactams) do not avidly bind to the penicillin-binding proteins of this pathogen.".
- Q423787 atcPrefix "J01".
- Q423787 atcSuffix "CA12".
- Q423787 bioavailability "0.0".
- Q423787 casNumber "61477-96-1".
- Q423787 chEBI "8232".
- Q423787 drugbank "DB00319".
- Q423787 fdaUniiCode "9I628532GX".
- Q423787 iupacName "(2S,5R,6R)-6-{[(2R)-2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-phenyl-acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid".
- Q423787 pubchem "43672".
- Q423787 thumbnail Piperacillin.svg?width=300.
- Q423787 wikiPageWikiLink Q15252755.
- Q423787 wikiPageWikiLink Q306264.
- Q423787 wikiPageWikiLink Q310286.
- Q423787 wikiPageWikiLink Q311379.
- Q423787 wikiPageWikiLink Q3425168.
- Q423787 wikiPageWikiLink Q432083.
- Q423787 wikiPageWikiLink Q595158.
- Q423787 wikiPageWikiLink Q597889.
- Q423787 wikiPageWikiLink Q640448.
- Q423787 wikiPageWikiLink Q7197337.
- Q423787 wikiPageWikiLink Q7214382.
- Q423787 wikiPageWikiLink Q7215865.
- Q423787 wikiPageWikiLink Q7369691.
- Q423787 wikiPageWikiLink Q7900376.
- Q423787 wikiPageWikiLink Q8264664.
- Q423787 wikiPageWikiLink Q8412954.
- Q423787 wikiPageWikiLink Q857288.
- Q423787 atcPrefix "J01".
- Q423787 atcSuffix "CA12".
- Q423787 bioavailability "0".
- Q423787 casNumber "61477".
- Q423787 chebi "8232".
- Q423787 drugbank "DB00319".
- Q423787 iupacName "-6".
- Q423787 pubchem "43672".
- Q423787 unii "9".
- Q423787 type ChemicalSubstance.
- Q423787 type Drug.
- Q423787 type ChemicalObject.
- Q423787 type Thing.
- Q423787 type Q8386.
- Q423787 comment "Piperacillin is a broad-spectrum β-lactam antibiotic of the ureidopenicillin class. The chemical structure of piperacillin and other ureidopenicillins incorporates a polar side chain that enhances penetration into Gram-(-) bacteria and reduces susceptibility to cleavage by Gram-(-) beta lactamase enzymes. These properties confer activity against the important hospital pathogen Pseudomonas aeruginosa.".
- Q423787 label "Piperacillin".
- Q423787 depiction Piperacillin.svg.
