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- Q421368 subject Q7145095.
- Q421368 subject Q7469560.
- Q421368 subject Q8529178.
- Q421368 subject Q8556415.
- Q421368 abstract "Iproniazid (Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class. It was discontinued in most of the world in the 1960s, but remained in use in France up until fairly recently.Iproniazid was originally developed for the treatment of tuberculosis, but in 1952, its antidepressant properties were discovered when researchers noted that patients given isoniazid became inappropriately happy. Subsequently N-isopropyl addition led to development as an antidepressant and was approved for use in 1958. It was withdrawn a few years later in 1961 due to a high incidence of hepatitis, and was replaced by less hepatotoxic drugs such as phenelzine and isocarboxazid.Although iproniazid was one of the first antidepressants ever marketed, amphetamine (marketed as Benzedrine from 1935, for "mild depression", amid other indications) predates it; and frankincense has been marketed traditionally for millennia for, among other things, altering mood, although it was not until 2012 that one of the components of its smoke was found to have antidepressant effects in mice.".
- Q421368 atcPrefix "N06".
- Q421368 atcSuffix "AF05".
- Q421368 casNumber "54-92-2".
- Q421368 drugbank "DB04818".
- Q421368 fdaUniiCode "D892HFI3XA".
- Q421368 iupacName "N'-isopropylisonicotinohydrazide".
- Q421368 pubchem "3748".
- Q421368 thumbnail Iproniazid.svg?width=300.
- Q421368 wikiPageWikiLink Q12204.
- Q421368 wikiPageWikiLink Q131742.
- Q421368 wikiPageWikiLink Q1349821.
- Q421368 wikiPageWikiLink Q142.
- Q421368 wikiPageWikiLink Q173486.
- Q421368 wikiPageWikiLink Q1747559.
- Q421368 wikiPageWikiLink Q179452.
- Q421368 wikiPageWikiLink Q2359711.
- Q421368 wikiPageWikiLink Q409595.
- Q421368 wikiPageWikiLink Q410954.
- Q421368 wikiPageWikiLink Q423169.
- Q421368 wikiPageWikiLink Q427492.
- Q421368 wikiPageWikiLink Q58447.
- Q421368 wikiPageWikiLink Q5954496.
- Q421368 wikiPageWikiLink Q7145095.
- Q421368 wikiPageWikiLink Q7469560.
- Q421368 wikiPageWikiLink Q76560.
- Q421368 wikiPageWikiLink Q8529178.
- Q421368 wikiPageWikiLink Q8556415.
- Q421368 atcPrefix "N06".
- Q421368 atcSuffix "AF05".
- Q421368 casNumber "54".
- Q421368 drugbank "DB04818".
- Q421368 iupacName "N'-isopropylisonicotinohydrazide".
- Q421368 pubchem "3748".
- Q421368 unii "D892HFI3XA".
- Q421368 type ChemicalSubstance.
- Q421368 type Drug.
- Q421368 type ChemicalObject.
- Q421368 type Thing.
- Q421368 type Q8386.
- Q421368 comment "Iproniazid (Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class. It was discontinued in most of the world in the 1960s, but remained in use in France up until fairly recently.Iproniazid was originally developed for the treatment of tuberculosis, but in 1952, its antidepressant properties were discovered when researchers noted that patients given isoniazid became inappropriately happy.".
- Q421368 label "Iproniazid".
- Q421368 depiction Iproniazid.svg.