Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q419215> ?p ?o }
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- Q419215 subject Q8819605.
- Q419215 abstract "Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA).On 13 May 2013, Servier released a Direct Healthcare Professional Communication which stated that new restrictions for the use of strontium ranelate are now in place, as randomised trials have shown an increased risk of myocardial infarction. Servier states that the use is now restricted to treatment of severe osteoporosis in postmenopausal women at high risk for fracture. The European Pharmacovigilance Risk Assessment Committee (PRAC) recommends restriction in the use of strontium ranelate, based on a routine benefit-risk assessment of the medicine, which included data showing an increased risk of heart problems, including heart attacks. On 21 February 2014 the European Medicine Agency recommended that strontium ranelate remain available with restrictions relative to patients with existing heart disease.".
- Q419215 atcPrefix "M05".
- Q419215 atcSuffix "BX03".
- Q419215 bioavailability "25.0".
- Q419215 casNumber "135459-90-4".
- Q419215 fdaUniiCode "04NQ160FRU".
- Q419215 iupacName "3-(2-oxido-2-oxoethyl)thiophene-2-carboxylate".
- Q419215 iupacName "distrontium 5-[bis(2-oxido-2-oxoethyl)amino]-4-cyano-".
- Q419215 pubchem "6918182".
- Q419215 thumbnail Strontium_ranelate.svg?width=300.
- Q419215 wikiPageExternalLink printerfriendlynews.php?newsid=132149.
- Q419215 wikiPageExternalLink news_detail_002005.jsp&mid=WC0b01ac058004d5c1.
- Q419215 wikiPageExternalLink www.protelos.com.
- Q419215 wikiPageWikiLink Q12152.
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- Q419215 wikiPageWikiLink Q6431240.
- Q419215 wikiPageWikiLink Q706.
- Q419215 wikiPageWikiLink Q828410.
- Q419215 wikiPageWikiLink Q86.
- Q419215 wikiPageWikiLink Q8819605.
- Q419215 wikiPageWikiLink Q907487.
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- Q419215 wikiPageWikiLink Q918396.
- Q419215 wikiPageWikiLink Q9377.
- Q419215 wikiPageWikiLink Q938.
- Q419215 atcPrefix "M05".
- Q419215 atcSuffix "BX03".
- Q419215 bioavailability "25.0".
- Q419215 casNumber "135459".
- Q419215 iupacName "3".
- Q419215 iupacName "distrontium 5-[bisamino]-4-cyano-".
- Q419215 pubchem "6918182".
- Q419215 unii "4".
- Q419215 type ChemicalSubstance.
- Q419215 type Drug.
- Q419215 type ChemicalObject.
- Q419215 type Thing.
- Q419215 type Q8386.
- Q419215 comment "Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts.".
- Q419215 label "Strontium ranelate".
- Q419215 depiction Strontium_ranelate.svg.
- Q419215 homepage www.protelos.com.
