Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q414904> ?p ?o }
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- Q414904 subject Q8652865.
- Q414904 subject Q8965786.
- Q414904 abstract "Aliskiren (INN) (trade names Tekturna, US; Rasilez, UK and elsewhere) is the first in a class of drugs called direct renin inhibitors. Its current licensed indication is essential (primary) hypertension. While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.In December 2011, Novartis halted a clinical trial of the drug after discovering increased incidence of nonfatal stroke, kidney complications, high blood potassium, and low blood pressure in people with diabetes and kidney impairment.As a result, in April 20, 2012: A new contraindication was added to the product label concerning the use of aliskiren with angiotensin receptor blockers (ARBs) or angiotensin-converting enzyme inhibitors (ACEIs) in patients with diabetes because of the risk of kidney impairment, low blood pressure, and high levels of potassium in the blood. A warning to avoid use of aliskiren with ARBs or ACEIs was also added for patients with moderate to severe kidney impairment (i.e., where glomerular filtration rate is less than 60 ml/min).Aliskiren was co-developed by the Swiss pharmaceutical companies Novartis and Speedel.".
- Q414904 atcPrefix "C09".
- Q414904 atcSuffix "XA02".
- Q414904 atcSupplemental "(withHCT)".
- Q414904 casNumber "173334-57-1".
- Q414904 chEBI "601027".
- Q414904 drugbank "DB01258".
- Q414904 fdaUniiCode "502FWN4Q32".
- Q414904 iupacName "(2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide".
- Q414904 pubchem "5493444".
- Q414904 thumbnail Aliskiren_Structural_Formulae_V.1.svg?width=300.
- Q414904 wikiPageExternalLink 8_0_ckrklsueyytkdcvb.html.
- Q414904 wikiPageExternalLink tekturna.pdf.
- Q414904 wikiPageWikiLink Q105522.
- Q414904 wikiPageWikiLink Q1067506.
- Q414904 wikiPageWikiLink Q1129007.
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- Q414904 wikiPageWikiLink Q213511.
- Q414904 wikiPageWikiLink Q262581.
- Q414904 wikiPageWikiLink Q2736135.
- Q414904 wikiPageWikiLink Q275419.
- Q414904 wikiPageWikiLink Q285044.
- Q414904 wikiPageWikiLink Q288280.
- Q414904 wikiPageWikiLink Q367700.
- Q414904 wikiPageWikiLink Q388801.
- Q414904 wikiPageWikiLink Q409255.
- Q414904 wikiPageWikiLink Q410061.
- Q414904 wikiPageWikiLink Q411229.
- Q414904 wikiPageWikiLink Q423930.
- Q414904 wikiPageWikiLink Q507154.
- Q414904 wikiPageWikiLink Q605259.
- Q414904 wikiPageWikiLink Q668093.
- Q414904 wikiPageWikiLink Q736715.
- Q414904 wikiPageWikiLink Q824258.
- Q414904 wikiPageWikiLink Q8652865.
- Q414904 wikiPageWikiLink Q8965786.
- Q414904 wikiPageWikiLink Q898218.
- Q414904 wikiPageWikiLink Q9368.
- Q414904 wikiPageWikiLink Q9377.
- Q414904 wikiPageWikiLink Q988405.
- Q414904 atcPrefix "9.0".
- Q414904 atcSuffix "XA02".
- Q414904 casNumber "173334".
- Q414904 chebi "601027".
- Q414904 drugbank "DB01258".
- Q414904 iupacName "-5".
- Q414904 pubchem "5493444".
- Q414904 unii "502".
- Q414904 type ChemicalSubstance.
- Q414904 type Drug.
- Q414904 type ChemicalObject.
- Q414904 type Thing.
- Q414904 type Q8386.
- Q414904 comment "Aliskiren (INN) (trade names Tekturna, US; Rasilez, UK and elsewhere) is the first in a class of drugs called direct renin inhibitors. Its current licensed indication is essential (primary) hypertension.".
- Q414904 label "Aliskiren".
- Q414904 depiction Aliskiren_Structural_Formulae_V.1.svg.