Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q4062649> ?p ?o }
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- Q4062649 subject Q52309.
- Q4062649 subject Q6938881.
- Q4062649 subject Q7334131.
- Q4062649 subject Q8645495.
- Q4062649 subject Q9134654.
- Q4062649 abstract "Allylprodine is an opioid analgesic that is an analog of prodine. It was discovered in by Hoffman-La Roche in 1957 during research into the related drug pethidine. Derivatives were tested to prove the theory that phenolic & non-phenolic opioids bind at different sites of the opiate receptor.Allylprodine is more potent as an analgesic than similar drugs such as α-prodine, and the 3R,4S-isomer is 23 times more potent than morphine, due to the allyl group binding to an additional amino acid target in the binding site on the μ-opioid receptor. It is also stereoselective, with one isomer being much more active. When modeled in three dimensions, the alkene overlays the alkenes found in 14-cinnamoyloxycodeinone and in 14-allyloxycodeinone, re-enforcing the presence of an interaction of the alkene.Allylprodine produces similar effects to other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.Allylprodine is regulated in most countries as is morphine, including being in Schedule I of the US Controlled Substances Act 1970 as a Narcotic with ACSCN 9602 and a 2014 annual aggregate manufacturing quota of 2 grammes.".
- Q4062649 atcPrefix "none".
- Q4062649 casNumber "25384-17-2".
- Q4062649 drugbank "DB01542".
- Q4062649 fdaUniiCode "4343OEZ18O".
- Q4062649 iupacName "(1-Methyl-4-phenyl-3-prop-2-enylpiperidin-4-yl) propanoate".
- Q4062649 pubchem "32938".
- Q4062649 thumbnail Allylprodine.svg?width=300.
- Q4062649 wikiPageWikiLink Q127076.
- Q4062649 wikiPageWikiLink Q127950.
- Q4062649 wikiPageWikiLink Q14911924.
- Q4062649 wikiPageWikiLink Q1641494.
- Q4062649 wikiPageWikiLink Q173235.
- Q4062649 wikiPageWikiLink Q186889.
- Q4062649 wikiPageWikiLink Q199602.
- Q4062649 wikiPageWikiLink Q423777.
- Q4062649 wikiPageWikiLink Q427523.
- Q4062649 wikiPageWikiLink Q4346433.
- Q4062649 wikiPageWikiLink Q4549579.
- Q4062649 wikiPageWikiLink Q485014.
- Q4062649 wikiPageWikiLink Q52309.
- Q4062649 wikiPageWikiLink Q55434.
- Q4062649 wikiPageWikiLink Q574801.
- Q4062649 wikiPageWikiLink Q6938881.
- Q4062649 wikiPageWikiLink Q7334131.
- Q4062649 wikiPageWikiLink Q8645495.
- Q4062649 wikiPageWikiLink Q9134654.
- Q4062649 atcPrefix "none".
- Q4062649 casNumber "25384".
- Q4062649 drugbank "DB01542".
- Q4062649 iupacName "propanoate".
- Q4062649 pubchem "32938".
- Q4062649 unii "4343".
- Q4062649 type ChemicalSubstance.
- Q4062649 type Drug.
- Q4062649 type ChemicalObject.
- Q4062649 type Thing.
- Q4062649 type Q8386.
- Q4062649 comment "Allylprodine is an opioid analgesic that is an analog of prodine. It was discovered in by Hoffman-La Roche in 1957 during research into the related drug pethidine.".
- Q4062649 label "Allylprodine".
- Q4062649 depiction Allylprodine.svg.