Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q3604498> ?p ?o }
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- Q3604498 subject Q7139608.
- Q3604498 subject Q7215865.
- Q3604498 subject Q8297699.
- Q3604498 subject Q8341873.
- Q3604498 subject Q8503574.
- Q3604498 abstract "Ajulemic acid (AB-III-56, HU-239, IP-751, CPL 7075, CT-3, Resunab) is a synthetic cannabinoid derivative of the non-psychoactive THC metabolite 11-nor-9-carboxy-THC that shows useful analgesic and anti-inflammatory effects without causing a subjective "high". It is being developed for the treatment of neuropathic pain and inflammatory conditions such as arthritis. It does not however share the anti-emetic effects of other cannabinoids but may be useful for treating pain and chronic inflammatory conditions where nausea is not present. Side effects include dry mouth, tiredness and dizziness. The mechanism of action has not yet been fully established, but ajulemic acid may activate the CB2 receptor in the periphery leading to production of resolving eicosanoids. Studies in animals at doses up to 40 mg/kg show minimal psychoactivity of ajulemic acid, comparable to that produced by tetrahydrocannabinol,. Likewise, there was no difference between ajulemic acid and placebo on the "cannabimimetic" assay when used in humans at therapeutic doses. A new highly purified composition of ajulemic acid named Resunab is being developed by Corbus Pharmaceuticals (formerly JB Therapeutics)for the treatment of orphan life-threatening inflammatory diseases.".
- Q3604498 atcPrefix "none".
- Q3604498 casNumber "137945-48-3".
- Q3604498 fdaUniiCode "OGN7X90BT8".
- Q3604498 iupacName "(6aR,10aR)-3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-Dibenzo(b,d)pyran-9-carboxylic acid".
- Q3604498 pubchem "3083542".
- Q3604498 thumbnail Ajulemicacid.png?width=300.
- Q3604498 wikiPageWikiLink Q170990.
- Q3604498 wikiPageWikiLink Q173235.
- Q3604498 wikiPageWikiLink Q17907844.
- Q3604498 wikiPageWikiLink Q190067.
- Q3604498 wikiPageWikiLink Q273499.
- Q3604498 wikiPageWikiLink Q407595.
- Q3604498 wikiPageWikiLink Q422936.
- Q3604498 wikiPageWikiLink Q575136.
- Q3604498 wikiPageWikiLink Q581996.
- Q3604498 wikiPageWikiLink Q7139608.
- Q3604498 wikiPageWikiLink Q7215865.
- Q3604498 wikiPageWikiLink Q8297699.
- Q3604498 wikiPageWikiLink Q8341873.
- Q3604498 wikiPageWikiLink Q8503574.
- Q3604498 wikiPageWikiLink Q945238.
- Q3604498 atcPrefix "none".
- Q3604498 casNumber "137945".
- Q3604498 iupacName "-3".
- Q3604498 pubchem "3083542".
- Q3604498 unii "OGN7X90BT8".
- Q3604498 type ChemicalSubstance.
- Q3604498 type Drug.
- Q3604498 type ChemicalObject.
- Q3604498 type Thing.
- Q3604498 type Q8386.
- Q3604498 comment "Ajulemic acid (AB-III-56, HU-239, IP-751, CPL 7075, CT-3, Resunab) is a synthetic cannabinoid derivative of the non-psychoactive THC metabolite 11-nor-9-carboxy-THC that shows useful analgesic and anti-inflammatory effects without causing a subjective "high". It is being developed for the treatment of neuropathic pain and inflammatory conditions such as arthritis.".
- Q3604498 label "Ajulemic acid".
- Q3604498 depiction Ajulemicacid.png.