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- Q3306175 subject Q7211373.
- Q3306175 abstract "Mepolizumab (trade name Nucala) is a humanized monoclonal antibody that recognizes interleukin-5 (IL-5).Mepolizumab has been investigated or is under investigation for the treatment of severe eosinophilic asthma, atopic dermatitis, hypereosinophilic syndrome (HES), eosinophilic esophagitis (EoE), nasal polyposis, eosinophilic granulomatosis with polyangiitis (EGPA) (i.e., Churg Strauss syndrome), and chronic obstructive pulmonary disease (COPD). Phase III clinical trials in severe eosinophilic asthma were completed in 2014.Mepolizumab is approved by the U.S. Food and Drug Administration (FDA) for the maintenance treatment of severe asthma in patients aged 12 years or older and with an eosinophilic phenotype in combination with other medicines used to treat asthma.The European Commission granted a marketing authorisation valid throughout the European Union on 2 December 2015. In Europe Nucala is indicated as an add-on treatment for severe refractory eosinophilic asthma in adult patients.".
- Q3306175 atcPrefix "L04".
- Q3306175 atcSuffix "AC06".
- Q3306175 casNumber "196078-29-2".
- Q3306175 drugbank "DB06612".
- Q3306175 fdaUniiCode "90Z2UF0E52".
- Q3306175 wikiPageWikiLink Q14877650.
- Q3306175 wikiPageWikiLink Q199804.
- Q3306175 wikiPageWikiLink Q204711.
- Q3306175 wikiPageWikiLink Q2057356.
- Q3306175 wikiPageWikiLink Q2551272.
- Q3306175 wikiPageWikiLink Q268667.
- Q3306175 wikiPageWikiLink Q32811.
- Q3306175 wikiPageWikiLink Q35869.
- Q3306175 wikiPageWikiLink Q422248.
- Q3306175 wikiPageWikiLink Q458.
- Q3306175 wikiPageWikiLink Q5939625.
- Q3306175 wikiPageWikiLink Q7211373.
- Q3306175 wikiPageWikiLink Q8055111.
- Q3306175 wikiPageWikiLink Q8880.
- Q3306175 atcPrefix "L04".
- Q3306175 atcSuffix "AC06".
- Q3306175 casNumber "196078".
- Q3306175 drugbank "DB06612".
- Q3306175 unii "90".
- Q3306175 type ChemicalSubstance.
- Q3306175 type Drug.
- Q3306175 type ChemicalObject.
- Q3306175 type Thing.
- Q3306175 type Q8386.
- Q3306175 comment "Mepolizumab (trade name Nucala) is a humanized monoclonal antibody that recognizes interleukin-5 (IL-5).Mepolizumab has been investigated or is under investigation for the treatment of severe eosinophilic asthma, atopic dermatitis, hypereosinophilic syndrome (HES), eosinophilic esophagitis (EoE), nasal polyposis, eosinophilic granulomatosis with polyangiitis (EGPA) (i.e., Churg Strauss syndrome), and chronic obstructive pulmonary disease (COPD).".
- Q3306175 label "Mepolizumab".