Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q2620206> ?p ?o }
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- Q2620206 subject Q8390819.
- Q2620206 subject Q8639167.
- Q2620206 subject Q9052781.
- Q2620206 abstract "Imiglucerase is a medication used in the treatment of Gaucher's disease.It is a recombinant DNA-produced analogue of human β-glucocerebrosidase.Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is givenintravenously after reconstitution as a treatment for Type 1 Gaucher's disease. It is available in formulations containing 200 or 400 units per vial. The specific activity of highly purified human enzyme is 890,000 units/mg. A typical dose is 2.5U/kg every two weeks, up to a maximum of 60 U/kg once every two weeks, and safety has been established from ages 2 and up. It is one of the most expensive drugs sold, with an annual cost to U.S. patients of $200,000. Due to the low profitability (and high expense) of developing medications for rare conditions, imiglucerase has been granted orphan drug status in the USA, Australia, and Japan.Cerezyme was one of the drugs manufactured at Genzyme's Allston, Massachusetts plant, for which production was disrupted in 2009 after contamination with Vesivirus 2117.".
- Q2620206 atcPrefix "A16".
- Q2620206 atcSuffix "AB02".
- Q2620206 casNumber "143003-46-7".
- Q2620206 drugbank "DB00053".
- Q2620206 fdaUniiCode "Q6U6J48BWY".
- Q2620206 iupacName "Human Beta-glucocerebrosidase".
- Q2620206 wikiPageWikiLink Q1367466.
- Q2620206 wikiPageWikiLink Q14878770.
- Q2620206 wikiPageWikiLink Q1502740.
- Q2620206 wikiPageWikiLink Q21011224.
- Q2620206 wikiPageWikiLink Q21396373.
- Q2620206 wikiPageWikiLink Q285697.
- Q2620206 wikiPageWikiLink Q425911.
- Q2620206 wikiPageWikiLink Q485014.
- Q2620206 wikiPageWikiLink Q640448.
- Q2620206 wikiPageWikiLink Q723912.
- Q2620206 wikiPageWikiLink Q8390819.
- Q2620206 wikiPageWikiLink Q861645.
- Q2620206 wikiPageWikiLink Q8639167.
- Q2620206 wikiPageWikiLink Q898365.
- Q2620206 wikiPageWikiLink Q9052781.
- Q2620206 atcPrefix "A16".
- Q2620206 atcSuffix "AB02".
- Q2620206 casNumber "143003".
- Q2620206 drugbank "DB00053".
- Q2620206 iupacName "Human Beta-glucocerebrosidase".
- Q2620206 unii "Q6U6J48BWY".
- Q2620206 type ChemicalSubstance.
- Q2620206 type Drug.
- Q2620206 type ChemicalObject.
- Q2620206 type Thing.
- Q2620206 type Q8386.
- Q2620206 comment "Imiglucerase is a medication used in the treatment of Gaucher's disease.It is a recombinant DNA-produced analogue of human β-glucocerebrosidase.Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is givenintravenously after reconstitution as a treatment for Type 1 Gaucher's disease. It is available in formulations containing 200 or 400 units per vial. The specific activity of highly purified human enzyme is 890,000 units/mg.".
- Q2620206 label "Imiglucerase".