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- Q2610084 subject Q6902503.
- Q2610084 subject Q7214339.
- Q2610084 subject Q8257056.
- Q2610084 abstract "Sideroblastic anemia or sideroachrestic anemia is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin, which red blood cells need to transport oxygen efficiently. The disorder may be caused either by a genetic disorder or indirectly as part of myelodysplastic syndrome, which can evolve into hematological malignancies (especially acute myelogenous leukemia). Sideroblasts (sidero- + -blast) are atypical, abnormal nucleated erythroblasts (precursors to mature red blood cells) with granules of iron accumulated in the mitochondria surrounding the nucleus. Normally, sideroblasts are present in the bone marrow, and enter the circulation after maturing into a normal erythrocyte.Ring sideroblasts are named so because iron-laden mitochondria form a ring around the nucleus. To count a cell as a ring sideroblast, the ring must encircle a third or more of the nucleus and contain five or more iron granules, according to the 2008 WHO classification of the tumors of the hematopoietic and lymphoid tissues.The WHO International Working Group on Morphology of MDS (IWGM-MDS) defined three types of sideroblasts: Type 1 sideroblasts: fewer than 5 siderotic granules in the cytoplasmType 2 sideroblasts: 5 or more siderotic granules, but not in a perinuclear distributionType 3 or ring sideroblasts: 5 or more granules in a perinuclear position, surrounding the nucleus or encompassing at least one third of the nuclear circumference.↑ ↑ ↑ ↑".
- Q2610084 icd10 "D64.0-D64.3".
- Q2610084 icd9 "285.0".
- Q2610084 meshId "D000756".
- Q2610084 omim "301310".
- Q2610084 thumbnail Sideroblast.png?width=300.
- Q2610084 wikiPageExternalLink sideroblastic.html.
- Q2610084 wikiPageExternalLink Sideroblastic.asp.
- Q2610084 wikiPageExternalLink br.fcgi?book=gene&part=sider-anemia.
- Q2610084 wikiPageExternalLink www.rareanemias.webs.com.
- Q2610084 wikiPageExternalLink www.sideroblasticanemia.org.
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- Q2610084 wikiPageWikiLink Q6902503.
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- Q2610084 icd "285".
- Q2610084 icd "D64.0-D64.3".
- Q2610084 meshid "D000756".
- Q2610084 name "Sideroblastic anemia".
- Q2610084 omim "301310".
- Q2610084 type Disease.
- Q2610084 type Thing.
- Q2610084 type Q12136.
- Q2610084 comment "Sideroblastic anemia or sideroachrestic anemia is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin, which red blood cells need to transport oxygen efficiently.".
- Q2610084 label "Sideroblastic anemia".
- Q2610084 depiction Sideroblast.png.
- Q2610084 name "Sideroblastic anemia".