Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q2387553> ?p ?o }
Showing triples 1 to 36 of
36
with 100 triples per page.
- Q2387553 subject Q7116685.
- Q2387553 subject Q8256351.
- Q2387553 subject Q8965786.
- Q2387553 subject Q9052323.
- Q2387553 abstract "Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention.The proposed indication for tafenoquine is for treatment of the hypnozoite stages of Plasmodium vivax and Plasmodium ovale that are responsible for relapse of these malaria species even when the blood stages are successfully cleared. This is only now achieved by administration of daily primaquine for 14 days. The main advantage of tafenoquine is that it has a long half-life (2–3 weeks) and therefore a single treatment may be sufficient to clear hypnozoites. The shorter regimen has been described as an advantage.Like primaquine, tafenoquine causes hemolysis in people with G-6-P deficiency. Indeed, the long half-life of tafenoquine suggests that particular care should be taken to ensure that individuals with severe G-6-P deficiency do not receive the drug.The dose of tafenoquine has not been firmly established, but for the treatment of Plasmodium vivax malaria, a dose of 800 mg over three days has been used.".
- Q2387553 atcPrefix "none".
- Q2387553 casNumber "106635-80-7".
- Q2387553 fdaUniiCode "262P8GS9L9".
- Q2387553 iupacName "N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine".
- Q2387553 pubchem "115358".
- Q2387553 thumbnail Tafenoquine.svg?width=300.
- Q2387553 wikiPageWikiLink Q130948.
- Q2387553 wikiPageWikiLink Q134445.
- Q2387553 wikiPageWikiLink Q212322.
- Q2387553 wikiPageWikiLink Q311376.
- Q2387553 wikiPageWikiLink Q419834.
- Q2387553 wikiPageWikiLink Q4644259.
- Q2387553 wikiPageWikiLink Q471706.
- Q2387553 wikiPageWikiLink Q7116685.
- Q2387553 wikiPageWikiLink Q8256351.
- Q2387553 wikiPageWikiLink Q848343.
- Q2387553 wikiPageWikiLink Q8965786.
- Q2387553 wikiPageWikiLink Q9052323.
- Q2387553 atcPrefix "none".
- Q2387553 casNumber "106635".
- Q2387553 iupacName "N-[2,6-Dimethoxy-4-methyl-5-[3-phenoxy]quinolin-8-yl]pentane-1,4-diamine".
- Q2387553 pubchem "115358".
- Q2387553 unii "262".
- Q2387553 type ChemicalSubstance.
- Q2387553 type Drug.
- Q2387553 type ChemicalObject.
- Q2387553 type Thing.
- Q2387553 type Q8386.
- Q2387553 comment "Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention.The proposed indication for tafenoquine is for treatment of the hypnozoite stages of Plasmodium vivax and Plasmodium ovale that are responsible for relapse of these malaria species even when the blood stages are successfully cleared. This is only now achieved by administration of daily primaquine for 14 days.".
- Q2387553 label "Tafenoquine".
- Q2387553 depiction Tafenoquine.svg.