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- Q2359590 subject Q15147502.
- Q2359590 subject Q7335351.
- Q2359590 subject Q9052323.
- Q2359590 abstract "Trifluridine (also called trifluorothymidine or TFT) is an anti-herpesvirus antiviral drug, used primarily on the eye. It was sold under the trade name, Viroptic, by Glaxo Wellcome, now merged into GlaxoSmithKline. The brand is now owned by Monarch Pharmaceuticals, which is wholly owned by King Pharmaceuticals.It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the -CF3 group added to the uracil component blocks base pairing, thus interfering with DNA replication.It is a component of the experimental anti-cancer drug TAS-102.A Cochrane Systematic Review showed that trifluridine was a more effective treatment than idoxuridine or vidarabine, significantly increasing the relative number of successfully healed eyes in 14 days.".
- Q2359590 atcPrefix "S01".
- Q2359590 atcSuffix "AD02".
- Q2359590 casNumber "70-00-8".
- Q2359590 chEBI "75179".
- Q2359590 drugbank "DB00432".
- Q2359590 fdaUniiCode "RMW9V5RW38".
- Q2359590 iupacName "1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5- (trifluoromethyl) pyrimidine-2,4-dione".
- Q2359590 pubchem "6256".
- Q2359590 thumbnail Trifluridine_structure.svg?width=300.
- Q2359590 wikiPageExternalLink Trifluridine_us_en.pdf.
- Q2359590 wikiPageWikiLink Q1105202.
- Q2359590 wikiPageWikiLink Q130996.
- Q2359590 wikiPageWikiLink Q145911.
- Q2359590 wikiPageWikiLink Q149348.
- Q2359590 wikiPageWikiLink Q15147502.
- Q2359590 wikiPageWikiLink Q15708335.
- Q2359590 wikiPageWikiLink Q1741688.
- Q2359590 wikiPageWikiLink Q182990.
- Q2359590 wikiPageWikiLink Q212322.
- Q2359590 wikiPageWikiLink Q2689559.
- Q2359590 wikiPageWikiLink Q409765.
- Q2359590 wikiPageWikiLink Q415107.
- Q2359590 wikiPageWikiLink Q419140.
- Q2359590 wikiPageWikiLink Q430024.
- Q2359590 wikiPageWikiLink Q7335351.
- Q2359590 wikiPageWikiLink Q846227.
- Q2359590 wikiPageWikiLink Q9052323.
- Q2359590 atcPrefix "S01".
- Q2359590 atcSuffix "AD02".
- Q2359590 casNumber "70".
- Q2359590 chebi "75179".
- Q2359590 drugbank "DB00432".
- Q2359590 iupacName "1".
- Q2359590 pubchem "6256".
- Q2359590 unii "RMW9V5RW38".
- Q2359590 type ChemicalSubstance.
- Q2359590 type Drug.
- Q2359590 type ChemicalObject.
- Q2359590 type Thing.
- Q2359590 type Q8386.
- Q2359590 comment "Trifluridine (also called trifluorothymidine or TFT) is an anti-herpesvirus antiviral drug, used primarily on the eye. It was sold under the trade name, Viroptic, by Glaxo Wellcome, now merged into GlaxoSmithKline.".
- Q2359590 label "Trifluridine".
- Q2359590 depiction Trifluridine_structure.svg.