Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q21098847> ?p ?o }
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- Q21098847 subject Q7404399.
- Q21098847 subject Q8334725.
- Q21098847 abstract "Verucerfont (GSK-561,679) is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist. Corticotropin releasing factor (CRF), also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is released in response to various triggers such as chronic stress, and activates the two corticotropin-releasing hormone receptors CRH-1 and CRH-2. This then triggers the release of corticotropin (ACTH), another hormone which is involved in the physiological response to stress. Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress. It is under investigation as a potential treatment for alcoholism, as chronic stress is often a factor in both development of alcoholism and relapse in recovering alcoholics. It has shown promising results in animal studies but has not been tested in humans.".
- Q21098847 atcPrefix "none".
- Q21098847 casNumber "885220-61-1".
- Q21098847 fdaUniiCode "X60608B091".
- Q21098847 iupacName "3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine".
- Q21098847 pubchem "11596613".
- Q21098847 thumbnail Verucerfont_structure.png?width=300.
- Q21098847 wikiPageWikiLink Q14819907.
- Q21098847 wikiPageWikiLink Q15326.
- Q21098847 wikiPageWikiLink Q18021818.
- Q21098847 wikiPageWikiLink Q185690.
- Q21098847 wikiPageWikiLink Q212322.
- Q21098847 wikiPageWikiLink Q3305232.
- Q21098847 wikiPageWikiLink Q4770927.
- Q21098847 wikiPageWikiLink Q5173294.
- Q21098847 wikiPageWikiLink Q5173297.
- Q21098847 wikiPageWikiLink Q7179563.
- Q21098847 wikiPageWikiLink Q7404399.
- Q21098847 wikiPageWikiLink Q8334725.
- Q21098847 atcPrefix "none".
- Q21098847 casNumber "885220".
- Q21098847 iupacName "3".
- Q21098847 pubchem "11596613".
- Q21098847 unii "X60608B091".
- Q21098847 type ChemicalSubstance.
- Q21098847 type Drug.
- Q21098847 type ChemicalObject.
- Q21098847 type Thing.
- Q21098847 type Q8386.
- Q21098847 comment "Verucerfont (GSK-561,679) is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist. Corticotropin releasing factor (CRF), also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is released in response to various triggers such as chronic stress, and activates the two corticotropin-releasing hormone receptors CRH-1 and CRH-2.".
- Q21098847 label "Verucerfont".
- Q21098847 depiction Verucerfont_structure.png.