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- Q209188 subject Q13246695.
- Q209188 subject Q6811985.
- Q209188 subject Q8919936.
- Q209188 subject Q8965786.
- Q209188 abstract "2,4,5-Trichlorophenoxyacetic acid (also known as 2,4,5-T), a synthetic auxin, is a chlorophenoxy acetic acid herbicide used to defoliate broad-leafed plants. It was developed in the late 1940s and was widely used in the agricultural industry until being phased out, starting in the late 1970s due to toxicity concerns. Agent Orange, a defoliant used by the British in the Malayan Emergency and the U.S. in the Vietnam War, was equal parts 2,4,5-T and 2,4-D (2,4-dichlorophenoxyacetic acid). 2,4,5-T itself is toxic with a NOAEL of 3 mg/kg/day and a LOAEL of 10 mg/kg/day. Additionally, the manufacturing process for 2,4,5-T contaminates this chemical with trace amounts of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD is a carcinogenic persistent organic pollutant with long-term effects on the environment. With proper temperature control during production of 2,4,5-T, TCDD levels can be held to about .005 ppm. Before the TCDD risk was well-understood, early production facilities lacked proper temperature controls and individual batches tested later were found to have as much as 60 ppm of TCDD.In 1970, the United States Department of Agriculture halted the use of 2,4,5-T on all food crops except rice, and in 1985, the EPA terminated all remaining uses in the U.S. of this herbicide. The international trade of 2,4,5-T is restricted by the Rotterdam Convention. 2,4,5-T has since largely been replaced by dicamba and triclopyr.Human health effects from 2,4,5-T at low environmental doses or at biomonitored levels from low environmental exposures are unknown. Intentional overdoses and unintentional high dose occupational exposures to chlorophenoxy acid herbicides have resulted in weakness, headache, dizziness, nausea, abdominal pain, myotonia, hypotension, renal and hepatic injury, and delayed neuropathy.IARC considers the chlorophenoxyacetic acids group of chemicals as possibly carcinogenic to humans.".
- Q209188 iupacName "(2,4,5-Trichlorophenoxy)acetic acid".
- Q209188 thumbnail 2,4,5-Trichlorophenoxyacetic_acid_structure_numbered.svg?width=300.
- Q209188 wikiPageExternalLink npgd0583.html.
- Q209188 wikiPageExternalLink Detail_Chemical.jsp?Rec_Id=PC34514.
- Q209188 wikiPageWikiLink Q13246695.
- Q209188 wikiPageWikiLink Q178266.
- Q209188 wikiPageWikiLink Q187661.
- Q209188 wikiPageWikiLink Q190022.
- Q209188 wikiPageWikiLink Q209222.
- Q209188 wikiPageWikiLink Q215946.
- Q209188 wikiPageWikiLink Q2303660.
- Q209188 wikiPageWikiLink Q2354629.
- Q209188 wikiPageWikiLink Q424684.
- Q209188 wikiPageWikiLink Q460173.
- Q209188 wikiPageWikiLink Q501542.
- Q209188 wikiPageWikiLink Q52822.
- Q209188 wikiPageWikiLink Q53744.
- Q209188 wikiPageWikiLink Q552168.
- Q209188 wikiPageWikiLink Q6811985.
- Q209188 wikiPageWikiLink Q8740.
- Q209188 wikiPageWikiLink Q8919936.
- Q209188 wikiPageWikiLink Q8965786.
- Q209188 wikiPageWikiLink Q912951.
- Q209188 wikiPageWikiLink Q94947.
- Q209188 iupacname "acetic acid".
- Q209188 name "245".
- Q209188 type ChemicalCompound.
- Q209188 type ChemicalSubstance.
- Q209188 type ChemicalObject.
- Q209188 type Thing.
- Q209188 type Q11173.
- Q209188 comment "2,4,5-Trichlorophenoxyacetic acid (also known as 2,4,5-T), a synthetic auxin, is a chlorophenoxy acetic acid herbicide used to defoliate broad-leafed plants. It was developed in the late 1940s and was widely used in the agricultural industry until being phased out, starting in the late 1970s due to toxicity concerns. Agent Orange, a defoliant used by the British in the Malayan Emergency and the U.S. in the Vietnam War, was equal parts 2,4,5-T and 2,4-D (2,4-dichlorophenoxyacetic acid).".
- Q209188 label "2,4,5-Trichlorophenoxyacetic acid".
- Q209188 depiction 2,4,5-Trichlorophenoxyacetic_acid_structure_numbered.svg.
- Q209188 name "2,4,5-Trichlorophenoxyacetic acid".