Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q19597740> ?p ?o }
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- Q19597740 subject Q20870725.
- Q19597740 subject Q7579524.
- Q19597740 subject Q8569934.
- Q19597740 subject Q8616491.
- Q19597740 subject Q8661590.
- Q19597740 subject Q8672733.
- Q19597740 subject Q8795906.
- Q19597740 subject Q8919936.
- Q19597740 abstract "Licostinel (INN) (code name ACEA-1021) is a competitive, silent antagonist of the glycine site of the NMDA receptor (Kb = 5 nM). It was under investigation by Acea Pharmaceuticals as a neuroprotective agent for the treatment of cerebral ischemia associated with stroke and head injuries but was ultimately never marketed. In clinical trials, licostinel did not produce phencyclidine-like psychotomimetic effects at the doses tested, though transient sedation, dizziness, and nausea were observed. In addition to its actions at the NMDA receptor, licostinel also acts as an antagonist of the AMPA and kainate receptors at high concentrations (Kb = 0.9 µM and 2.5 µM, respectively).".
- Q19597740 atcPrefix "None".
- Q19597740 casNumber "153504-81-5".
- Q19597740 iupacName "6,7-Dichloro-5-nitro-1,4-dihydro-2,3-quinoxalinedione".
- Q19597740 pubchem "5486198".
- Q19597740 thumbnail Licostinel.svg?width=300.
- Q19597740 wikiPageWikiLink Q10916362.
- Q19597740 wikiPageWikiLink Q12202.
- Q19597740 wikiPageWikiLink Q186889.
- Q19597740 wikiPageWikiLink Q1981368.
- Q19597740 wikiPageWikiLink Q20870725.
- Q19597740 wikiPageWikiLink Q2920572.
- Q19597740 wikiPageWikiLink Q295251.
- Q19597740 wikiPageWikiLink Q30612.
- Q19597740 wikiPageWikiLink Q3454536.
- Q19597740 wikiPageWikiLink Q407324.
- Q19597740 wikiPageWikiLink Q410943.
- Q19597740 wikiPageWikiLink Q414896.
- Q19597740 wikiPageWikiLink Q4782250.
- Q19597740 wikiPageWikiLink Q4862390.
- Q19597740 wikiPageWikiLink Q5156356.
- Q19597740 wikiPageWikiLink Q5361298.
- Q19597740 wikiPageWikiLink Q5528046.
- Q19597740 wikiPageWikiLink Q574801.
- Q19597740 wikiPageWikiLink Q6695177.
- Q19597740 wikiPageWikiLink Q7256512.
- Q19597740 wikiPageWikiLink Q7448341.
- Q19597740 wikiPageWikiLink Q7579524.
- Q19597740 wikiPageWikiLink Q824258.
- Q19597740 wikiPageWikiLink Q8569934.
- Q19597740 wikiPageWikiLink Q8616491.
- Q19597740 wikiPageWikiLink Q8661590.
- Q19597740 wikiPageWikiLink Q8672733.
- Q19597740 wikiPageWikiLink Q8795906.
- Q19597740 wikiPageWikiLink Q8919936.
- Q19597740 atcPrefix "None".
- Q19597740 casNumber "153504".
- Q19597740 iupacName "67".
- Q19597740 pubchem "5486198".
- Q19597740 type ChemicalSubstance.
- Q19597740 type Drug.
- Q19597740 type ChemicalObject.
- Q19597740 type Thing.
- Q19597740 type Q8386.
- Q19597740 comment "Licostinel (INN) (code name ACEA-1021) is a competitive, silent antagonist of the glycine site of the NMDA receptor (Kb = 5 nM). It was under investigation by Acea Pharmaceuticals as a neuroprotective agent for the treatment of cerebral ischemia associated with stroke and head injuries but was ultimately never marketed. In clinical trials, licostinel did not produce phencyclidine-like psychotomimetic effects at the doses tested, though transient sedation, dizziness, and nausea were observed.".
- Q19597740 label "Licostinel".
- Q19597740 depiction Licostinel.svg.