Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q18047575> ?p ?o }
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- Q18047575 subject Q7091706.
- Q18047575 abstract "Voltage-gated hydrogen channel 1 is a protein that in humans is encoded by the HVCN1 gene.Voltage-gated hydrogen channel 1 is a voltage-gated proton channel that has been shown to allow proton transport into phagosomes and out of many types of cells including spermatozoa, electrically excitable cells and respiratory epithelial cells. The proton-conducting HVCN1 channel has only transmembrane domains corresponding to the S1-S4 voltage sensing domains (VSD) of voltage-gated potassium channels and voltage-gated sodium channels. Molecular simulation is consistent with a water-filled pore that can function as a "water wire" for allowing hydrogen bonded H+ to cross the membrane. However, mutation of Asp112 in human Hv1 results in anion permeation, suggesting that obligatory protonation of Asp produces proton selectivity. Quantum mechanical calculations show that the Asp-Arg interaction can produce proton selective permeation. The HVCN1 protein has been shown to exist as a dimer with two functioning pores. Like other VSD channels, HVCN1 channels conduct ions about 1000-fold slower than channels formed by tetrameric S5-S6 central pores.".
- Q18047575 entrezgene "84329".
- Q18047575 wikiPageWikiLink Q11269508.
- Q18047575 wikiPageWikiLink Q1428754.
- Q18047575 wikiPageWikiLink Q194277.
- Q18047575 wikiPageWikiLink Q1988322.
- Q18047575 wikiPageWikiLink Q424960.
- Q18047575 wikiPageWikiLink Q581996.
- Q18047575 wikiPageWikiLink Q7091706.
- Q18047575 wikiPageWikiLink Q7187.
- Q18047575 wikiPageWikiLink Q74560.
- Q18047575 wikiPageWikiLink Q7940729.
- Q18047575 wikiPageWikiLink Q8054.
- Q18047575 wikiPageWikiLink Q901955.
- Q18047575 wikiPageWikiLink Q903234.
- Q18047575 wikiPageWikiLink Q974135.
- Q18047575 type Biomolecule.
- Q18047575 type Protein.
- Q18047575 type Thing.
- Q18047575 type Q206229.
- Q18047575 type Q8054.
- Q18047575 comment "Voltage-gated hydrogen channel 1 is a protein that in humans is encoded by the HVCN1 gene.Voltage-gated hydrogen channel 1 is a voltage-gated proton channel that has been shown to allow proton transport into phagosomes and out of many types of cells including spermatozoa, electrically excitable cells and respiratory epithelial cells.".
- Q18047575 label "HVCN1".