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- Q18033808 subject Q6984021.
- Q18033808 abstract "GTP-binding protein Di-Ras3 (DIRAS3) also known as aplysia ras homology member I (ARHI) is a protein that in humans is encoded by the DIRAS3 gene.This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.It is maternally imprinted, and is linked to breast cancer as well as ovarian cancer. The ARHI gene includes one promoter, two exons and one intron with a 687 bp protein-coding region that encodes a 26-kDa protein. The ARHI protein (italic for gene, nonitalic for protein) is a GTPase belonging to the Ras superfamily and shares 50-60% homology with Ras and Rap, two other small GTP binding proteins. This gene is a maternally imprinted putative tumor suppressor, and reduced expression of ARHI has been reported in 70% of invasive breast cancers.".
- Q18033808 entrezgene "9077".
- Q18033808 wikiPageWikiLink Q128581.
- Q18033808 wikiPageWikiLink Q14197552.
- Q18033808 wikiPageWikiLink Q145911.
- Q18033808 wikiPageWikiLink Q14902453.
- Q18033808 wikiPageWikiLink Q15311861.
- Q18033808 wikiPageWikiLink Q172341.
- Q18033808 wikiPageWikiLink Q178430.
- Q18033808 wikiPageWikiLink Q181619.
- Q18033808 wikiPageWikiLink Q218642.
- Q18033808 wikiPageWikiLink Q224527.
- Q18033808 wikiPageWikiLink Q26939.
- Q18033808 wikiPageWikiLink Q284398.
- Q18033808 wikiPageWikiLink Q387059.
- Q18033808 wikiPageWikiLink Q409125.
- Q18033808 wikiPageWikiLink Q41301.
- Q18033808 wikiPageWikiLink Q620730.
- Q18033808 wikiPageWikiLink Q6984021.
- Q18033808 wikiPageWikiLink Q7187.
- Q18033808 wikiPageWikiLink Q7294687.
- Q18033808 wikiPageWikiLink Q769143.
- Q18033808 wikiPageWikiLink Q8054.
- Q18033808 wikiPageWikiLink Q8066.
- Q18033808 wikiPageWikiLink Q84087.
- Q18033808 wikiPageWikiLink Q898273.
- Q18033808 type Biomolecule.
- Q18033808 type Protein.
- Q18033808 type Thing.
- Q18033808 type Q206229.
- Q18033808 type Q8054.
- Q18033808 comment "GTP-binding protein Di-Ras3 (DIRAS3) also known as aplysia ras homology member I (ARHI) is a protein that in humans is encoded by the DIRAS3 gene.This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression.".
- Q18033808 label "DIRAS3 (gene)".