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- Q18030934 abstract "Tyrosine-protein phosphatase non-receptor type 13 is an enzyme that in humans is encoded by the PTPN13 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as IkappaBalpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.".
- Q18030934 entrezgene "5783".
- Q18030934 wikiPageWikiLink Q133226.
- Q18030934 wikiPageWikiLink Q154626.
- Q18030934 wikiPageWikiLink Q1637543.
- Q18030934 wikiPageWikiLink Q18030778.
- Q18030934 wikiPageWikiLink Q189159.
- Q18030934 wikiPageWikiLink Q20970154.
- Q18030934 wikiPageWikiLink Q210861.
- Q18030934 wikiPageWikiLink Q210973.
- Q18030934 wikiPageWikiLink Q2565229.
- Q18030934 wikiPageWikiLink Q307446.
- Q18030934 wikiPageWikiLink Q310425.
- Q18030934 wikiPageWikiLink Q643602.
- Q18030934 wikiPageWikiLink Q7187.
- Q18030934 wikiPageWikiLink Q8047.
- Q18030934 wikiPageWikiLink Q896177.
- Q18030934 wikiPageWikiLink Q901100.
- Q18030934 type Biomolecule.
- Q18030934 type Protein.
- Q18030934 type Thing.
- Q18030934 type Q206229.
- Q18030934 type Q8054.
- Q18030934 comment "Tyrosine-protein phosphatase non-receptor type 13 is an enzyme that in humans is encoded by the PTPN13 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.".
- Q18030934 label "PTPN13".