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- Q17912191 abstract "CYP8B1 (cytochrome P450, family 8, subfamily B, polypeptide 1) also known as sterol 12-alpha-hydroxylase is a protein which in humans is encoded by the CYP8B1 gene.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP8B1 is an endoplasmic reticulum membrane protein and catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of the two primary bile acids, cholic acid and chenodeoxycholic acid, both of which are secreted in the bile. In the intestine these bile acids affect the solubility of cholesterol and other lipids, promoting their absorption. CYP8B1 is unique among the cytochrome P450 genes in that it is intronless.".
- Q17912191 entrezgene "1582".
- Q17912191 wikiPageWikiLink Q207551.
- Q17912191 wikiPageWikiLink Q287415.
- Q17912191 wikiPageWikiLink Q407693.
- Q17912191 wikiPageWikiLink Q413288.
- Q17912191 wikiPageWikiLink Q419028.
- Q17912191 wikiPageWikiLink Q43656.
- Q17912191 wikiPageWikiLink Q4644247.
- Q17912191 wikiPageWikiLink Q6901821.
- Q17912191 wikiPageWikiLink Q7187.
- Q17912191 wikiPageWikiLink Q79927.
- Q17912191 wikiPageWikiLink Q8054.
- Q17912191 type Biomolecule.
- Q17912191 type Protein.
- Q17912191 type Thing.
- Q17912191 type Q206229.
- Q17912191 type Q8054.
- Q17912191 comment "CYP8B1 (cytochrome P450, family 8, subfamily B, polypeptide 1) also known as sterol 12-alpha-hydroxylase is a protein which in humans is encoded by the CYP8B1 gene.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.".
- Q17912191 label "CYP8B1".