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- Q17832920 abstract "Sodium/potassium-transporting ATPase subunit alpha-1 is an enzyme that in humans is encoded by the ATP1A1 gene.The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+-ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.In melanocytic cells ATP1A1 gene expression may be regulated by MITF.".
- Q17832920 entrezgene "476".
- Q17832920 symbol "H-K_ATPase_N".
- Q17832920 thumbnail PDB_1iwc_EBI.jpg?width=300.
- Q17832920 wikiPageWikiLink Q11903647.
- Q17832920 wikiPageWikiLink Q14906495.
- Q17832920 wikiPageWikiLink Q174211.
- Q17832920 wikiPageWikiLink Q187126.
- Q17832920 wikiPageWikiLink Q190065.
- Q17832920 wikiPageWikiLink Q211026.
- Q17832920 wikiPageWikiLink Q272741.
- Q17832920 wikiPageWikiLink Q29548.
- Q17832920 wikiPageWikiLink Q300033.
- Q17832920 wikiPageWikiLink Q304618.
- Q17832920 wikiPageWikiLink Q36496.
- Q17832920 wikiPageWikiLink Q41861.
- Q17832920 wikiPageWikiLink Q423042.
- Q17832920 wikiPageWikiLink Q59143.
- Q17832920 wikiPageWikiLink Q609809.
- Q17832920 wikiPageWikiLink Q658.
- Q17832920 wikiPageWikiLink Q703.
- Q17832920 wikiPageWikiLink Q7187.
- Q17832920 wikiPageWikiLink Q7365.
- Q17832920 wikiPageWikiLink Q8047.
- Q17832920 wikiPageWikiLink Q8054.
- Q17832920 wikiPageWikiLink Q82264.
- Q17832920 wikiPageWikiLink Q909456.
- Q17832920 wikiPageWikiLink Q911011.
- Q17832920 wikiPageWikiLink Q9620.
- Q17832920 symbol "H-K_ATPase_N".
- Q17832920 type Biomolecule.
- Q17832920 type Protein.
- Q17832920 type Thing.
- Q17832920 type Q206229.
- Q17832920 type Q8054.
- Q17832920 comment "Sodium/potassium-transporting ATPase subunit alpha-1 is an enzyme that in humans is encoded by the ATP1A1 gene.The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane.".
- Q17832920 label "ATPase, Na+/K+ transporting, alpha 1".
- Q17832920 depiction PDB_1iwc_EBI.jpg.
