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- Q17149132 subject Q7063424.
- Q17149132 subject Q8414607.
- Q17149132 subject Q9094579.
- Q17149132 abstract "ParvE101Q is an experimental modification of parvalbumin, designed to delay calcium sequestration in heart muscles to enhance contraction. The protein parvalbumin has EF hand motifs used for calcium binding. EF hands are structural helix-loop-helix protein subunits that have a high affinity for calcium ions, and a moderate affinity for magnesium ions. In muscle, the binding of Ca2+ by parvalbumin efficiently sequesters it following contraction. This increases the speed of muscle relaxation, allowing the muscle to contract again sooner. Although parvalbumin is classified as a delayed calcium buffer, it quickly sequesters Ca2+, usually before the muscle is done fully contracting. Large amounts of parvalbumin allow rapid contractions of muscles at a high contractile speed with the trade-off of having relatively lower contraction force. This decreased force of contraction is due to the rapid sequestration of Ca2+, preventing prolonged contraction which is required for greater force.".
- Q17149132 wikiPageWikiLink Q1072.
- Q17149132 wikiPageWikiLink Q1073.
- Q17149132 wikiPageWikiLink Q170545.
- Q17149132 wikiPageWikiLink Q178450.
- Q17149132 wikiPageWikiLink Q181003.
- Q17149132 wikiPageWikiLink Q181136.
- Q17149132 wikiPageWikiLink Q181619.
- Q17149132 wikiPageWikiLink Q181754.
- Q17149132 wikiPageWikiLink Q188941.
- Q17149132 wikiPageWikiLink Q189933.
- Q17149132 wikiPageWikiLink Q218642.
- Q17149132 wikiPageWikiLink Q2720322.
- Q17149132 wikiPageWikiLink Q41861.
- Q17149132 wikiPageWikiLink Q428914.
- Q17149132 wikiPageWikiLink Q4383200.
- Q17149132 wikiPageWikiLink Q487844.
- Q17149132 wikiPageWikiLink Q497232.
- Q17149132 wikiPageWikiLink Q5018814.
- Q17149132 wikiPageWikiLink Q5018841.
- Q17149132 wikiPageWikiLink Q5272105.
- Q17149132 wikiPageWikiLink Q60235.
- Q17149132 wikiPageWikiLink Q660.
- Q17149132 wikiPageWikiLink Q706.
- Q17149132 wikiPageWikiLink Q7063424.
- Q17149132 wikiPageWikiLink Q79927.
- Q17149132 wikiPageWikiLink Q8066.
- Q17149132 wikiPageWikiLink Q8414607.
- Q17149132 wikiPageWikiLink Q899814.
- Q17149132 wikiPageWikiLink Q9094579.
- Q17149132 wikiPageWikiLink Q9404.
- Q17149132 comment "ParvE101Q is an experimental modification of parvalbumin, designed to delay calcium sequestration in heart muscles to enhance contraction. The protein parvalbumin has EF hand motifs used for calcium binding. EF hands are structural helix-loop-helix protein subunits that have a high affinity for calcium ions, and a moderate affinity for magnesium ions. In muscle, the binding of Ca2+ by parvalbumin efficiently sequesters it following contraction.".
- Q17149132 label "Parve101q".