Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q17094770> ?p ?o }
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- Q17094770 subject Q4925926.
- Q17094770 abstract "The enhanceosome is a higher-order protein complex assembled at the enhancer and regulates expression of a target gene. The binding and assembly of the activating proteins is cooperative due to energetically favorable protein-protein interactions formed in the complex.The best known example of the enhanceosome acts on the human interferon-beta gene, which is upregulated in cells that are infected by viruses. Three activator proteins - NF-κB, an interferon activator protein such as IRF-3, and the ATF-2/c-Jun complex - cooperatively bind to the upstream enhancer region upon viral infection. The interaction is mediated by a fourth protein HMG-I, which assists in stabilizing the complex by promoting inter-protein interactions. The assembled enhanceosome recruits transcriptional machinery such as RNA polymerase to the promoter region to initiate gene expression.".
- Q17094770 thumbnail Enhanceosome_vertical.png?width=300.
- Q17094770 wikiPageExternalLink mom_2010_2.
- Q17094770 wikiPageWikiLink Q14914339.
- Q17094770 wikiPageWikiLink Q26972.
- Q17094770 wikiPageWikiLink Q272631.
- Q17094770 wikiPageWikiLink Q411114.
- Q17094770 wikiPageWikiLink Q420927.
- Q17094770 wikiPageWikiLink Q4677459.
- Q17094770 wikiPageWikiLink Q4925926.
- Q17094770 wikiPageWikiLink Q5.
- Q17094770 wikiPageWikiLink Q6046488.
- Q17094770 wikiPageWikiLink Q7187.
- Q17094770 wikiPageWikiLink Q808.
- Q17094770 wikiPageWikiLink Q896177.
- Q17094770 wikiPageWikiLink Q913367.
- Q17094770 wikiPageWikiLink Q926211.
- Q17094770 comment "The enhanceosome is a higher-order protein complex assembled at the enhancer and regulates expression of a target gene. The binding and assembly of the activating proteins is cooperative due to energetically favorable protein-protein interactions formed in the complex.The best known example of the enhanceosome acts on the human interferon-beta gene, which is upregulated in cells that are infected by viruses.".
- Q17094770 label "Enhanceosome".
- Q17094770 depiction Enhanceosome_vertical.png.