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- Q16959658 subject Q7579524.
- Q16959658 subject Q8235519.
- Q16959658 subject Q8508620.
- Q16959658 subject Q8625430.
- Q16959658 subject Q8965786.
- Q16959658 abstract "Demecolcine, also known as colcemid, is a drug used in chemotherapy.It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic. It depolymerises microtubules and limits microtubule formation (inactivates spindle fibre formation), thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed.During cell division Demecolcine inhibits mitosis at metaphase by inhibiting spindle formation. Medically Demecolcine has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle.In animal cloning procedures Demecolcine makes an ovum eject its nucleus, creating space for insertion of a new nucleus.".
- Q16959658 atcPrefix "L01".
- Q16959658 atcSuffix "CC01".
- Q16959658 casNumber "477-30-5".
- Q16959658 fdaUniiCode "Z01IVE25KI".
- Q16959658 iupacName "(S)-1,2,3,10-Tetramethoxy-7-methylamino-6,7-dihydro-5H-benzo[a]heptalen-9-one".
- Q16959658 pubchem "2832".
- Q16959658 thumbnail Demecolcine.png?width=300.
- Q16959658 wikiPageWikiLink Q167198.
- Q16959658 wikiPageWikiLink Q189933.
- Q16959658 wikiPageWikiLink Q189967.
- Q16959658 wikiPageWikiLink Q282629.
- Q16959658 wikiPageWikiLink Q326224.
- Q16959658 wikiPageWikiLink Q4407.
- Q16959658 wikiPageWikiLink Q481808.
- Q16959658 wikiPageWikiLink Q574427.
- Q16959658 wikiPageWikiLink Q70702.
- Q16959658 wikiPageWikiLink Q7579524.
- Q16959658 wikiPageWikiLink Q7868.
- Q16959658 wikiPageWikiLink Q8235519.
- Q16959658 wikiPageWikiLink Q8508620.
- Q16959658 wikiPageWikiLink Q8625430.
- Q16959658 wikiPageWikiLink Q8965786.
- Q16959658 wikiPageWikiLink Q906487.
- Q16959658 wikiPageWikiLink Q974135.
- Q16959658 atcPrefix "L01".
- Q16959658 atcSuffix "CC01".
- Q16959658 casNumber "477".
- Q16959658 iupacName "-12310".
- Q16959658 pubchem "2832".
- Q16959658 unii "Z01IVE25KI".
- Q16959658 type ChemicalSubstance.
- Q16959658 type Drug.
- Q16959658 type ChemicalObject.
- Q16959658 type Thing.
- Q16959658 type Q8386.
- Q16959658 comment "Demecolcine, also known as colcemid, is a drug used in chemotherapy.It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic.".
- Q16959658 label "Demecolcine".
- Q16959658 depiction Demecolcine.png.