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- Q15708279 subject Q8462729.
- Q15708279 subject Q8621213.
- Q15708279 subject Q8832995.
- Q15708279 abstract "Technetium (99mTc) etarfolatide is an investigational non-invasive, folate receptor-targeting companion imaging agent that is being developed by Endocyte. Etarfolatide consists of a small molecule targeting the folate receptor and an imaging agent, which is based on technetium-99m. This companion imaging agent identifies cells expressing the folate receptor, including cancer and inflammatory cells. Etarfolatide is currently being investigated together with the corresponding small molecule drug conjugate (SMDC) vintafolide in a Phase 3 study in platinum-resistant ovarian cancer and in a Phase 2b study in non-small cell lung cancer. It identifies patients with metastases that are positive for the folate receptor and therefore more likely to respond to treatment with vintafolide. Other folate receptor targeting SMDCs for the treatment of cancer, inflammatory diseases and kidney disease are in preclinical development and will also utilize etarfolatide as companion imaging agent.The European Medicines Agency (EMA) is reviewing the Marketing Authorization Application (MAA) filings for both vintafolide and etarfolatide, for the treatment of patients with folate receptor-positive platinum-resistant ovarian cancer in combination with pegylated liposomal doxorubicin (PLD).".
- Q15708279 atcPrefix "V09".
- Q15708279 atcSuffix "IA08".
- Q15708279 casNumber "479410-20-3".
- Q15708279 iupacName "(2R)-2-[(2S)-2-[(2S)-3-[[(4R)-4-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]-4-carboxybutanoyl]amino]-2-azanidylpropanoyl]azanidyl-3-carboxypropanoyl]azanidyl-3-hydroxy-3-oxopropane-1-thiolate oxotechnetium(4+) (99mTc)".
- Q15708279 pubchem "71300440".
- Q15708279 thumbnail Technetium_etarfolatide.svg?width=300.
- Q15708279 wikiPageWikiLink Q12078.
- Q15708279 wikiPageWikiLink Q130146.
- Q15708279 wikiPageWikiLink Q17037259.
- Q15708279 wikiPageWikiLink Q17108676.
- Q15708279 wikiPageWikiLink Q172341.
- Q15708279 wikiPageWikiLink Q181876.
- Q15708279 wikiPageWikiLink Q18936.
- Q15708279 wikiPageWikiLink Q1988322.
- Q15708279 wikiPageWikiLink Q2373354.
- Q15708279 wikiPageWikiLink Q3658562.
- Q15708279 wikiPageWikiLink Q5464235.
- Q15708279 wikiPageWikiLink Q6770873.
- Q15708279 wikiPageWikiLink Q7932801.
- Q15708279 wikiPageWikiLink Q8462729.
- Q15708279 wikiPageWikiLink Q8621213.
- Q15708279 wikiPageWikiLink Q8832995.
- Q15708279 atcPrefix "V09".
- Q15708279 atcSuffix "IA08".
- Q15708279 casNumber "479410".
- Q15708279 drugName "Technetium etarfolatide".
- Q15708279 iupacName "-2".
- Q15708279 pubchem "71300440".
- Q15708279 type ChemicalSubstance.
- Q15708279 type Drug.
- Q15708279 type ChemicalObject.
- Q15708279 type Thing.
- Q15708279 type Q8386.
- Q15708279 comment "Technetium (99mTc) etarfolatide is an investigational non-invasive, folate receptor-targeting companion imaging agent that is being developed by Endocyte. Etarfolatide consists of a small molecule targeting the folate receptor and an imaging agent, which is based on technetium-99m. This companion imaging agent identifies cells expressing the folate receptor, including cancer and inflammatory cells.".
- Q15708279 label "Technetium (99mTc) etarfolatide".
- Q15708279 depiction Technetium_etarfolatide.svg.
- Q15708279 name "Technetium (99mTc) etarfolatide".