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- Q15409392 subject Q6184252.
- Q15409392 subject Q8376090.
- Q15409392 abstract "Metapramine (trade names Prodastene, Timaxel) is a tricyclic antidepressant (TCA) developed by Rhone Poulenc that was introduced for the treatment of depression in France in 1984. In addition to its efficacy against affective disorders, it also has analgesic properties, and may be useful in the treatment of pain.Metapramine has desipramine-like effects, acting as a norepinephrine reuptake inhibitor without affecting the reuptake of serotonin or dopamine. It has also been shown to act as a low-affinity NMDA receptor antagonist. Metapramine's direct effects on serotonin, histamine, and muscarinic acetylcholine receptors have not been assayed, but uniquely among most TCAs, it has anecdotally been reported to lack anticholinergic effects.".
- Q15409392 atcPrefix "none".
- Q15409392 casNumber "21730-16-5".
- Q15409392 fdaUniiCode "303954M7YF".
- Q15409392 iupacName "(±)-10,11-dihydro-N,5-dimethyl-5H-dibenz[b,f]azepin-10-amine".
- Q15409392 pubchem "65700".
- Q15409392 thumbnail Metapramine_skeletal.svg?width=300.
- Q15409392 wikiPageWikiLink Q113259.
- Q15409392 wikiPageWikiLink Q142.
- Q15409392 wikiPageWikiLink Q167934.
- Q15409392 wikiPageWikiLink Q170304.
- Q15409392 wikiPageWikiLink Q173235.
- Q15409392 wikiPageWikiLink Q188638.
- Q15409392 wikiPageWikiLink Q238516.
- Q15409392 wikiPageWikiLink Q4044974.
- Q15409392 wikiPageWikiLink Q410959.
- Q15409392 wikiPageWikiLink Q414896.
- Q15409392 wikiPageWikiLink Q423288.
- Q15409392 wikiPageWikiLink Q424228.
- Q15409392 wikiPageWikiLink Q42844.
- Q15409392 wikiPageWikiLink Q467717.
- Q15409392 wikiPageWikiLink Q6184252.
- Q15409392 wikiPageWikiLink Q81938.
- Q15409392 wikiPageWikiLink Q8376090.
- Q15409392 wikiPageWikiLink Q899107.
- Q15409392 wikiPageWikiLink Q899668.
- Q15409392 wikiPageWikiLink Q908843.
- Q15409392 wikiPageWikiLink Q910028.
- Q15409392 atcPrefix "none".
- Q15409392 casNumber "21730".
- Q15409392 iupacName "-1011".
- Q15409392 pubchem "65700".
- Q15409392 unii "303954".
- Q15409392 type ChemicalSubstance.
- Q15409392 type Drug.
- Q15409392 type ChemicalObject.
- Q15409392 type Thing.
- Q15409392 type Q8386.
- Q15409392 comment "Metapramine (trade names Prodastene, Timaxel) is a tricyclic antidepressant (TCA) developed by Rhone Poulenc that was introduced for the treatment of depression in France in 1984. In addition to its efficacy against affective disorders, it also has analgesic properties, and may be useful in the treatment of pain.Metapramine has desipramine-like effects, acting as a norepinephrine reuptake inhibitor without affecting the reuptake of serotonin or dopamine.".
- Q15409392 label "Metapramine".
- Q15409392 depiction Metapramine_skeletal.svg.