Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q12252367> ?p ?o }
- Q12252367 subject Q6853509.
- Q12252367 subject Q7014562.
- Q12252367 subject Q7060938.
- Q12252367 subject Q7215455.
- Q12252367 abstract "Atherosclerosis (also known as arteriosclerotic vascular disease or ASVD) is a specific form of arteriosclerosis in which an artery wall thickens as a result of invasion and accumulation of white blood cells (WBCs) (foam cell) and proliferation of intimal smooth muscle cell creating a fibrofatty plaque.The accumulation of the white blood cells is termed "fatty streaks" early on because of the appearance being similar to that of marbled steak. These accumulations contain both living, active WBCs (producing inflammation) and remnants of dead cells, including cholesterol and triglycerides. The remnants eventually include calcium and other crystallized materials within the outermost and oldest plaque. The "fatty streaks" reduce the elasticity of the artery walls. However, they do not affect blood flow for decades because the artery muscular wall enlarges at the locations of plaque. The wall stiffening may eventually increase pulse pressure; widened pulse pressure is one possible result of advanced disease within the major arteries.Atherosclerosis is therefore a syndrome affecting arterial blood vessels due to a chronic inflammatory response of WBCs in the walls of arteries. This is promoted by low-density lipoproteins (LDL, plasma proteins that carry cholesterol and triglycerides) without adequate removal of fats and cholesterol from the macrophages by functional high-density lipoproteins (HDL). It is commonly referred to as a "hardening" or furring of the arteries. It is caused by the formation of multiple atheromatous plaques within the arteries.The plaque is divided into three distinct components: The atheroma ("lump of gruel", REDIRECT Template:Etymology), which is the nodular accumulation of a soft, flaky, yellowish material at the center of large plaques, composed of macrophages nearest the lumen of the artery Underlying areas of cholesterol crystals Calcification at the outer base of older or more advanced lesions.Atherosclerosis is a chronic disease that remains asymptomatic for decades. Atherosclerotic lesions, or atherosclerotic plaques, are separated into two broad categories: Stable and unstable (also called vulnerable). The pathobiology of atherosclerotic lesions is very complicated, but generally, stable atherosclerotic plaques, which tend to be asymptomatic, are rich in extracellular matrix and smooth muscle cells. On the other hand, unstable plaques are rich in macrophages and foam cells, and the extracellular matrix separating the lesion from the arterial lumen (also known as the fibrous cap) is usually weak and prone to rupture. Ruptures of the fibrous cap expose thrombogenic material, such as collagen, to the circulation and eventually induce thrombus formation in the lumen. Upon formation, intraluminal thrombi can occlude arteries outright (e.g., coronary occlusion), but more often they detach, move into the circulation, and eventually occlude smaller downstream branches causing thromboembolism. Apart from thromboembolism, chronically expanding atherosclerotic lesions can cause complete closure of the lumen. Chronically expanding lesions are often asymptomatic until lumen stenosis is so severe (usually over 80%) that blood supply to downstream tissue(s) is insufficient, resulting in ischemia.These complications of advanced atherosclerosis are chronic, slowly progressive and cumulative. Most commonly, soft plaque suddenly ruptures (see vulnerable plaque), causing the formation of a thrombus that will rapidly slow or stop blood flow, leading to death of the tissues fed by the artery in approximately five minutes. This catastrophic event is called an infarction. One of the most common recognized scenarios is called coronary thrombosis of a coronary artery, causing myocardial infarction (a heart attack). The same process in an artery to the brain is commonly called stroke. Another common scenario in very advanced disease is claudication from insufficient blood supply to the legs. Atherosclerosis affects the entire artery tree, but mostly larger, high-pressure vessels such as the coronary, renal, femoral, cerebral, and carotid arteries. These are termed "clinically silent" because the person having the infarction does not notice the problem and does not seek medical help, or when they do, physicians do not recognize what has happened.".
- Q12252367 icd10 "I25.0,I25.1,I70".
- Q12252367 icd9 ",".
- Q12252367 icd9 "414.0".
- Q12252367 icd9 "440".
- Q12252367 meshId "D050197".
- Q12252367 thumbnail Endo_dysfunction_Athero.PNG?width=300.
- Q12252367 wikiPageExternalLink review-article-hypertension-and-pathogenesis-of-atherosclerosis.
- Q12252367 wikiPageExternalLink Home.aspx.
- Q12252367 wikiPageWikiLink Q101026.
- Q12252367 wikiPageWikiLink Q101991.
- Q12252367 wikiPageWikiLink Q1026509.
- Q12252367 wikiPageWikiLink Q103675.
- Q12252367 wikiPageWikiLink Q10379.
- Q12252367 wikiPageWikiLink Q105522.
- Q12252367 wikiPageWikiLink Q1058276.
- Q12252367 wikiPageWikiLink Q107244.
- Q12252367 wikiPageWikiLink Q107988.
- Q12252367 wikiPageWikiLink Q111140.
- Q12252367 wikiPageWikiLink Q1133904.
- Q12252367 wikiPageWikiLink Q11358.
- Q12252367 wikiPageWikiLink Q11367.
- Q12252367 wikiPageWikiLink Q1140549.
- Q12252367 wikiPageWikiLink Q1141325.
- Q12252367 wikiPageWikiLink Q12152.
- Q12252367 wikiPageWikiLink Q12174.
- Q12252367 wikiPageWikiLink Q12202.
- Q12252367 wikiPageWikiLink Q12206.
- Q12252367 wikiPageWikiLink Q132319.
- Q12252367 wikiPageWikiLink Q1325542.
- Q12252367 wikiPageWikiLink Q1329925.
- Q12252367 wikiPageWikiLink Q133087.
- Q12252367 wikiPageWikiLink Q133948.
- Q12252367 wikiPageWikiLink Q13405249.
- Q12252367 wikiPageWikiLink Q134658.
- Q12252367 wikiPageWikiLink Q1350700.
- Q12252367 wikiPageWikiLink Q1413651.
- Q12252367 wikiPageWikiLink Q1425962.
- Q12252367 wikiPageWikiLink Q1482382.
- Q12252367 wikiPageWikiLink Q1484346.
- Q12252367 wikiPageWikiLink Q14859861.
- Q12252367 wikiPageWikiLink Q14864092.
- Q12252367 wikiPageWikiLink Q14877233.
- Q12252367 wikiPageWikiLink Q14901827.
- Q12252367 wikiPageWikiLink Q14904270.
- Q12252367 wikiPageWikiLink Q149348.
- Q12252367 wikiPageWikiLink Q1501273.
- Q12252367 wikiPageWikiLink Q1588755.
- Q12252367 wikiPageWikiLink Q16501.
- Q12252367 wikiPageWikiLink Q1671577.
- Q12252367 wikiPageWikiLink Q16974010.
- Q12252367 wikiPageWikiLink Q1707292.
- Q12252367 wikiPageWikiLink Q17154669.
- Q12252367 wikiPageWikiLink Q1740954.
- Q12252367 wikiPageWikiLink Q175821.
- Q12252367 wikiPageWikiLink Q177708.
- Q12252367 wikiPageWikiLink Q178069.
- Q12252367 wikiPageWikiLink Q179217.
- Q12252367 wikiPageWikiLink Q179630.
- Q12252367 wikiPageWikiLink Q18028636.
- Q12252367 wikiPageWikiLink Q180762.
- Q12252367 wikiPageWikiLink Q18377123.
- Q12252367 wikiPageWikiLink Q184204.
- Q12252367 wikiPageWikiLink Q184559.
- Q12252367 wikiPageWikiLink Q185056.
- Q12252367 wikiPageWikiLink Q186319.
- Q12252367 wikiPageWikiLink Q186915.
- Q12252367 wikiPageWikiLink Q1872526.
- Q12252367 wikiPageWikiLink Q188151.
- Q12252367 wikiPageWikiLink Q189206.
- Q12252367 wikiPageWikiLink Q189389.
- Q12252367 wikiPageWikiLink Q192466.
- Q12252367 wikiPageWikiLink Q192864.
- Q12252367 wikiPageWikiLink Q193529.
- Q12252367 wikiPageWikiLink Q193825.
- Q12252367 wikiPageWikiLink Q2005375.
- Q12252367 wikiPageWikiLink Q205130.
- Q12252367 wikiPageWikiLink Q2070979.
- Q12252367 wikiPageWikiLink Q207550.
- Q12252367 wikiPageWikiLink Q208453.
- Q12252367 wikiPageWikiLink Q212354.
- Q12252367 wikiPageWikiLink Q2343082.
- Q12252367 wikiPageWikiLink Q243465.
- Q12252367 wikiPageWikiLink Q253817.
- Q12252367 wikiPageWikiLink Q261327.
- Q12252367 wikiPageWikiLink Q2661464.
- Q12252367 wikiPageWikiLink Q26868.
- Q12252367 wikiPageWikiLink Q2698596.
- Q12252367 wikiPageWikiLink Q2711291.
- Q12252367 wikiPageWikiLink Q28350.
- Q12252367 wikiPageWikiLink Q28749.
- Q12252367 wikiPageWikiLink Q2888709.
- Q12252367 wikiPageWikiLink Q3098624.
- Q12252367 wikiPageWikiLink Q311213.
- Q12252367 wikiPageWikiLink Q32566.
- Q12252367 wikiPageWikiLink Q3604509.