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- Q1138358 subject Q4926419.
- Q1138358 subject Q7217197.
- Q1138358 abstract "The CpG sites or CG sites are regions of DNA where a cytosine nucleotide is followed by a guanine nucleotide in the linear sequence of bases along its 5' → 3' direction. CpG is shorthand for 5'—C—phosphate—G—3' , that is, cytosine and guanine separated by only one phosphate; phosphate links any two nucleosides together in DNA. The CpG notation is used to distinguish this single-stranded linear sequence from the CG base-pairing of cytosine and guanine for double-stranded sequences. The CpG notation is therefore to be interpreted as the cytosine being 5 prime to the guanine base. CpG should not be confused with GpC, the latter meaning that a guanine is followed by a cytosine in the 5' → 3' direction of a single-stranded sequence.Cytosines in CpG dinucleotides can be methylated to form 5-methylcytosine. In mammals, methylating the cytosine within a gene can change its expression, a mechanism that is part of a larger field of science studying gene regulation that is called epigenetics. Enzymes that add a methyl group are called DNA methyltransferases.In mammals, 70% to 80% of CpG cytosines are methylated.Unmethylated CpG dinucleotide sites can be detected by Toll-like receptor 9 (TLR 9) on plasmacytoid dendritic cells, monocytes, natural killer (NK) cells, and B cells in humans. This is used to detect intracellular Viral infection.".
- Q1138358 thumbnail Cpg_islands.svg?width=300.
- Q1138358 wikiPageWikiLink Q1154602.
- Q1138358 wikiPageWikiLink Q12045567.
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- Q1138358 wikiPageWikiLink Q171973.
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- Q1138358 wikiPageWikiLink Q178425.
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- Q1138358 wikiPageWikiLink Q1995607.
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- Q1138358 wikiPageWikiLink Q224093.
- Q1138358 wikiPageWikiLink Q238563.
- Q1138358 wikiPageWikiLink Q26939.
- Q1138358 wikiPageWikiLink Q28734.
- Q1138358 wikiPageWikiLink Q28745.
- Q1138358 wikiPageWikiLink Q36293.
- Q1138358 wikiPageWikiLink Q3780824.
- Q1138358 wikiPageWikiLink Q412199.
- Q1138358 wikiPageWikiLink Q422445.
- Q1138358 wikiPageWikiLink Q4926419.
- Q1138358 wikiPageWikiLink Q5011010.
- Q1138358 wikiPageWikiLink Q518328.
- Q1138358 wikiPageWikiLink Q628025.
- Q1138358 wikiPageWikiLink Q7217197.
- Q1138358 wikiPageWikiLink Q7377.
- Q1138358 wikiPageWikiLink Q7430.
- Q1138358 wikiPageWikiLink Q8047.
- Q1138358 wikiPageWikiLink Q84087.
- Q1138358 wikiPageWikiLink Q863908.
- Q1138358 wikiPageWikiLink Q874745.
- Q1138358 wikiPageWikiLink Q933491.
- Q1138358 type Thing.
- Q1138358 comment "The CpG sites or CG sites are regions of DNA where a cytosine nucleotide is followed by a guanine nucleotide in the linear sequence of bases along its 5' → 3' direction. CpG is shorthand for 5'—C—phosphate—G—3' , that is, cytosine and guanine separated by only one phosphate; phosphate links any two nucleosides together in DNA. The CpG notation is used to distinguish this single-stranded linear sequence from the CG base-pairing of cytosine and guanine for double-stranded sequences.".
- Q1138358 label "CpG site".
- Q1138358 differentFrom Q477471.
- Q1138358 depiction Cpg_islands.svg.