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- Q1114116 subject Q8395760.
- Q1114116 abstract "Aspartate kinase (aspartokinase, aspartic kinase) is an enzyme that catalyzes the phosphorylation of the amino acid aspartate. This reaction is the first step in the biosynthesis of three essential amino acids: methionine, lysine, and threonine, known as the "aspartate family". The gene for aspartokinase is present only in microorganisms and plants; it is not present in animals, which must obtain aspartate-family amino acids in their diet.In Escherichia coli, aspartokinase is present as three independently regulated isozymes, each of which is specific to one of the three downstream biochemical pathways. This allows the independent regulation of the rates of methionine, lysine, and threonine production. The forms that produce threonine and lysine are subject to feedback inhibition, and all three can be repressed at the level of gene expression by high concentrations of their end-products. Absence from animals makes these enzymes key targets for new herbicides and biocides and for improvements in nutritional value of crops.This protein may use the morpheein model of allosteric regulation.".
- Q1114116 ecNumber "2.7.2.4".
- Q1114116 wikiPageWikiLink Q178430.
- Q1114116 wikiPageWikiLink Q178450.
- Q1114116 wikiPageWikiLink Q180341.
- Q1114116 wikiPageWikiLink Q186521.
- Q1114116 wikiPageWikiLink Q242736.
- Q1114116 wikiPageWikiLink Q245282.
- Q1114116 wikiPageWikiLink Q25419.
- Q1114116 wikiPageWikiLink Q26972.
- Q1114116 wikiPageWikiLink Q39833.
- Q1114116 wikiPageWikiLink Q407801.
- Q1114116 wikiPageWikiLink Q474191.
- Q1114116 wikiPageWikiLink Q5381546.
- Q1114116 wikiPageWikiLink Q6913367.
- Q1114116 wikiPageWikiLink Q7187.
- Q1114116 wikiPageWikiLink Q729.
- Q1114116 wikiPageWikiLink Q756.
- Q1114116 wikiPageWikiLink Q8047.
- Q1114116 wikiPageWikiLink Q8066.
- Q1114116 wikiPageWikiLink Q82264.
- Q1114116 wikiPageWikiLink Q8395760.
- Q1114116 wikiPageWikiLink Q845326.
- Q1114116 wikiPageWikiLink Q851162.
- Q1114116 ecNumber "2.7".
- Q1114116 name "Aspartate kinase".
- Q1114116 type Biomolecule.
- Q1114116 type Enzyme.
- Q1114116 type Thing.
- Q1114116 type Q206229.
- Q1114116 type Q8047.
- Q1114116 comment "Aspartate kinase (aspartokinase, aspartic kinase) is an enzyme that catalyzes the phosphorylation of the amino acid aspartate. This reaction is the first step in the biosynthesis of three essential amino acids: methionine, lysine, and threonine, known as the "aspartate family".".
- Q1114116 label "Aspartate kinase".
- Q1114116 name "Aspartate kinase".