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- fncel.2013.00218 author "Hayley S, Litteljohn D".
- fncel.2013.00218 date "2013".
- fncel.2013.00218 doi "10.3389/fncel.2013.00218".
- fncel.2013.00218 isCitedBy NRX-1074.
- fncel.2013.00218 journal "Front Cell Neurosci".
- fncel.2013.00218 pages "218".
- fncel.2013.00218 pmc "3834236".
- fncel.2013.00218 pmid "24312008".
- fncel.2013.00218 quote "Despite the mounting evidence indicating that ketamine has rapid and robust antidepressant properties , concerns over ketamine’s psychotomimetic effects have spurred intensive efforts to develop safer and more tolerable glutamate-based antidepressants. At the vanguard of this movement are the “next generation” NMDA receptor antagonists. Included here are the aminoadamantanes, memantine and amantadine ; the NR2B-selective antagonists, traxoprodil and MK-0657 ; and the low-affinity NMDA channel blocker AZD6765 . The NMDA receptor glycine-site functional partial agonist, GLYX-13, and its orally bioavailable and presumed more potent analog, NRX-1074, have also garnered the recent attention of researchers and clinicians , as have several modulators of metabotropic glutamate receptors and select α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor potentiators .".
- fncel.2013.00218 title "Neuroplasticity and the next wave of antidepressant strategies".
- fncel.2013.00218 volume "7".