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- Zebularine abstract "Zebularine is a nucleoside analog of cytidine. It is a \"transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.\"In a small study of mice with a defective Adenomatous polyposis coli gene, oral administration of zebularine to males had no effect on the overall methylation of DNA or the number of polyps, but in females the average number of polyps was reduced from 58 to 1. It has therefore been suggested for drug use as a prototype of epigenetic therapy for cancer chemoprevention.".
- Zebularine iupacName "1-(β-(D)-Ribofuranosyl)-2(1H)-pyrimidinone".
- Zebularine thumbnail Zebularine.svg?width=300.
- Zebularine wikiPageID "37422838".
- Zebularine wikiPageLength "2662".
- Zebularine wikiPageOutDegree "10".
- Zebularine wikiPageRevisionID "679121036".
- Zebularine wikiPageWikiLink Adenomatous_polyposis_coli.
- Zebularine wikiPageWikiLink Category:Nucleosides.
- Zebularine wikiPageWikiLink Category:Pyrimidones.
- Zebularine wikiPageWikiLink Chemoprophylaxis.
- Zebularine wikiPageWikiLink Cytidine.
- Zebularine wikiPageWikiLink Cytidine_deaminase.
- Zebularine wikiPageWikiLink DNA_methylation.
- Zebularine wikiPageWikiLink Epigenetic_therapy.
- Zebularine wikiPageWikiLink Nucleoside_analogue.
- Zebularine wikiPageWikiLink Transition_state_analog.
- Zebularine wikiPageWikiLinkText "Zebularine".
- Zebularine wikiPageWikiLinkText "zebularine".
- Zebularine imagefile "Zebularine.svg".
- Zebularine imagesize "200".
- Zebularine iupacname "1".
- Zebularine othernames "Pyrimidin-2-one β-(D)-ribofuranoside".
- Zebularine wikiPageUsesTemplate Template:Chembox.
- Zebularine wikiPageUsesTemplate Template:Chembox_Hazards.
- Zebularine wikiPageUsesTemplate Template:Chembox_Identifiers.
- Zebularine wikiPageUsesTemplate Template:Chembox_Properties.
- Zebularine wikiPageUsesTemplate Template:Clear-left.
- Zebularine wikiPageUsesTemplate Template:Double_image.
- Zebularine wikiPageUsesTemplate Template:Organic-compound-stub.
- Zebularine wikiPageUsesTemplate Template:Reflist.
- Zebularine subject Category:Nucleosides.
- Zebularine subject Category:Pyrimidones.
- Zebularine hypernym Analog.
- Zebularine type ChemicalCompound.
- Zebularine type ChemicalSubstance.
- Zebularine type Drug.
- Zebularine type Glycoside.
- Zebularine type Heterocycle.
- Zebularine type Ketone.
- Zebularine type Nucleoside.
- Zebularine type ChemicalObject.
- Zebularine type Thing.
- Zebularine type Q11173.
- Zebularine comment "Zebularine is a nucleoside analog of cytidine. It is a \"transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates.".
- Zebularine label "Zebularine".
- Zebularine sameAs Q8068322.
- Zebularine sameAs Zebularina.
- Zebularine sameAs m.0nb3n64.
- Zebularine sameAs Zebularin.
- Zebularine sameAs Zebularin.
- Zebularine sameAs Q8068322.
- Zebularine wasDerivedFrom Zebularine?oldid=679121036.
- Zebularine depiction Zebularine.svg.
- Zebularine isPrimaryTopicOf Zebularine.