Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Tiospirone> ?p ?o }
Showing triples 1 to 90 of
90
with 100 triples per page.
- Tiospirone abstract "Tiospirone (BMY-13,859), also sometimes called tiaspirone or tiosperone, is an atypical antipsychotic of the azapirone class. It was investigated as a treatment for schizophrenia in the late 1980s and was found to have an effectiveness equivalent to those of typical antipsychotics in clinical trials but without causing extrapyramidal side effects. However, development was halted and it was not marketed. Perospirone, another azapirone derivative with antipsychotic properties, was synthesized and assayed several years after tiospirone. It was found to be both more potent and more selective in comparison and was commercialized instead.Tiospirone acts as a 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2C, and 5-HT7 receptor inverse agonist, and D2, D4, and α1-adrenergic receptor antagonist.Binding profile".
- Tiospirone atcPrefix "none".
- Tiospirone casNumber "87691-91-6".
- Tiospirone fdaUniiCode "35C6UMO5SR".
- Tiospirone iupacName "8-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione".
- Tiospirone pubchem "55752".
- Tiospirone thumbnail Tiospirone.svg?width=300.
- Tiospirone wikiPageID "26160599".
- Tiospirone wikiPageLength "8050".
- Tiospirone wikiPageOutDegree "26".
- Tiospirone wikiPageRevisionID "694673859".
- Tiospirone wikiPageWikiLink 5-HT1A_receptor.
- Tiospirone wikiPageWikiLink 5-HT2A_receptor.
- Tiospirone wikiPageWikiLink 5-HT2C_receptor.
- Tiospirone wikiPageWikiLink 5-HT7_receptor.
- Tiospirone wikiPageWikiLink Alpha-1_adrenergic_receptor.
- Tiospirone wikiPageWikiLink Atypical_antipsychotic.
- Tiospirone wikiPageWikiLink Azapirone.
- Tiospirone wikiPageWikiLink Category:Abandoned_drugs.
- Tiospirone wikiPageWikiLink Category:Antipsychotics.
- Tiospirone wikiPageWikiLink Category:Azapirones.
- Tiospirone wikiPageWikiLink Category:Benzothiazoles.
- Tiospirone wikiPageWikiLink Category:Piperazines.
- Tiospirone wikiPageWikiLink Clinical_trial.
- Tiospirone wikiPageWikiLink Dopamine_receptor_D2.
- Tiospirone wikiPageWikiLink Dopamine_receptor_D4.
- Tiospirone wikiPageWikiLink Extrapyramidal_symptoms.
- Tiospirone wikiPageWikiLink Functional_selectivity.
- Tiospirone wikiPageWikiLink Inverse_agonist.
- Tiospirone wikiPageWikiLink Partial_agonist.
- Tiospirone wikiPageWikiLink Perospirone.
- Tiospirone wikiPageWikiLink Potency_(pharmacology).
- Tiospirone wikiPageWikiLink Receptor_antagonist.
- Tiospirone wikiPageWikiLink Schizophrenia.
- Tiospirone wikiPageWikiLink Side_effect.
- Tiospirone wikiPageWikiLink Typical_antipsychotic.
- Tiospirone wikiPageWikiLinkText "Tiospirone".
- Tiospirone wikiPageWikiLinkText "tiospirone".
- Tiospirone atcPrefix "none".
- Tiospirone c "24".
- Tiospirone casNumber "87691".
- Tiospirone chembl "35057".
- Tiospirone chemspiderid "50348".
- Tiospirone eliminationHalfLife "5040.0".
- Tiospirone excretion "Urine".
- Tiospirone h "32".
- Tiospirone iupacName "8".
- Tiospirone iupharLigand "101".
- Tiospirone legalStatus "Development terminated".
- Tiospirone metabolism "Hepatic".
- Tiospirone molecularWeight "440.6".
- Tiospirone n "4".
- Tiospirone o "2".
- Tiospirone pubchem "55752".
- Tiospirone s "1".
- Tiospirone unii "35".
- Tiospirone width "275".
- Tiospirone wikiPageUsesTemplate Template:Adrenergics.
- Tiospirone wikiPageUsesTemplate Template:Antipsychotics.
- Tiospirone wikiPageUsesTemplate Template:Dopaminergics.
- Tiospirone wikiPageUsesTemplate Template:Drugbox.
- Tiospirone wikiPageUsesTemplate Template:Fdacite.
- Tiospirone wikiPageUsesTemplate Template:Piperazines.
- Tiospirone wikiPageUsesTemplate Template:Reflist.
- Tiospirone wikiPageUsesTemplate Template:Serotonergics.
- Tiospirone subject Category:Abandoned_drugs.
- Tiospirone subject Category:Antipsychotics.
- Tiospirone subject Category:Azapirones.
- Tiospirone subject Category:Benzothiazoles.
- Tiospirone subject Category:Piperazines.
- Tiospirone type ChemicalSubstance.
- Tiospirone type Drug.
- Tiospirone type Antidepressant.
- Tiospirone type Drug.
- Tiospirone type Heterocycle.
- Tiospirone type Imide.
- Tiospirone type ChemicalObject.
- Tiospirone type Thing.
- Tiospirone type Q8386.
- Tiospirone comment "Tiospirone (BMY-13,859), also sometimes called tiaspirone or tiosperone, is an atypical antipsychotic of the azapirone class. It was investigated as a treatment for schizophrenia in the late 1980s and was found to have an effectiveness equivalent to those of typical antipsychotics in clinical trials but without causing extrapyramidal side effects. However, development was halted and it was not marketed.".
- Tiospirone label "Tiospirone".
- Tiospirone sameAs Q13415380.
- Tiospirone sameAs تیوسپیرون.
- Tiospirone sameAs m.0b6nxn4.
- Tiospirone sameAs Tiospiron.
- Tiospirone sameAs Tiospiron.
- Tiospirone sameAs Q13415380.
- Tiospirone wasDerivedFrom Tiospirone?oldid=694673859.
- Tiospirone depiction Tiospirone.svg.
- Tiospirone isPrimaryTopicOf Tiospirone.